17619-39-5

Basic information

• Product Name: 2-Methyl-1H-Pyrrole-3-carboxaldehyde
• Synonyms: 2-Methyl-1H-Pyrrole-3-carboxaldehyde;2-Methyl-1H-pyrrole-3-carbaldehyde
• CAS NO: 17619-39-5
• Molecular Formula: C₆H₇NO
• Molecular Weight: 109.12588
• Mol File: 17619-39-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Methyl-1H-Pyrrole-3-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-1H-Pyrrole-3-carboxaldehyde(17619-39-5)
• EPA Substance Registry System: 2-Methyl-1H-Pyrrole-3-carboxaldehyde(17619-39-5)

Safety Data

• Hazardous Substances Data: 17619-39-5(Hazardous Substances Data)

Upstream product

• 881675-63-4 [2-methyl-1-(phenylsulfonyl)-1H-pyrrol-3-yl]methanol 
• 881675-94-1 2-methyl-1-(phenylsulfonyl)-1H-pyrrole-3-carbaldehyde 
• 124647-46-7 N-(hydroxy-2' ethyl) amino-3 butene-2 oate d'ethyle 

Relevant articles and documents

Proton pump inhibitors

A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R 1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R 2 , R 3 and R 4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R 5 and R 6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof. or a prodrug thereof is provided.

PROTON PUMP INHIBITORS

A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R2, R3 and R4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R5 and R6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof. or a prodrug thereof is provided.

SYNTHESE DE PYRROLES ET D'OXAZOLES PAR PYROLYSE DE N-(HYDROXY-2' ETHYL) AMINO-3 PROPENOATE

The gas phas pyrolysis of various N-(2'-hydroxyethyl)-3-amino propenoates 1-6 and N-(2'-hydroxy-2'-phenyl ethyl)-3-amino propanoate 7-9 at 390 deg C-420 deg C leads respectively to formylpyrroles 11-16 and benzoylpyrroles 17-19 and, in some cases, to substituted oxazoles 36-39.The results are best explained by the intermediate formation of a dicarbonyl derivative followed either by an intramolecular thermal crotonisation or a six ? electrocyclization of an azomethine ylide.