17642-90-9 Usage
Description
2H-Azepine-2-thione, hexahydro-1-(phenylmethyl)-, also known as thiazepine, is a heterocyclic chemical compound with the molecular formula C13H17NOS. It features a seven-membered ring with a nitrogen atom and a sulfur atom, making it a unique and versatile molecule in the field of chemistry. 2H-Azepine-2-thione, hexahydro-1-(phenylmethyl)has garnered interest due to its potential applications in the pharmaceutical industry and its biological activities.
Uses
Used in Pharmaceutical Industry:
2H-Azepine-2-thione, hexahydro-1-(phenylmethyl)is utilized as a precursor in the synthesis of various drugs, particularly those targeting psychiatric disorders. Its unique structure allows for the development of molecules with specific therapeutic properties, making it a valuable component in medicinal chemistry.
Used in Drug Development for Psychiatric Disorders:
In the realm of psychiatric treatments, 2H-Azepine-2-thione, hexahydro-1-(phenylmethyl)serves as a key intermediate for creating pharmaceuticals that can address a range of mental health conditions. Its incorporation into drug molecules can lead to the design of more effective and targeted therapies for patients suffering from such disorders.
Used in Research for Biological Activities and Therapeutic Properties:
Beyond its practical applications, 2H-Azepine-2-thione, hexahydro-1-(phenylmethyl)is also studied for its inherent biological activities and potential therapeutic properties. This research can lead to a deeper understanding of how this compound interacts with biological systems and may uncover new avenues for its use in medicine and healthcare.
Check Digit Verification of cas no
The CAS Registry Mumber 17642-90-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,6,4 and 2 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17642-90:
(7*1)+(6*7)+(5*6)+(4*4)+(3*2)+(2*9)+(1*0)=119
119 % 10 = 9
So 17642-90-9 is a valid CAS Registry Number.
17642-90-9Relevant articles and documents
Reductive Alkylation of Tertiary Lactams via Addition of Organocopper (RCu) Reagents to Thioiminium Ions
Mateo, Pierre,Cinqualbre, Joséphine E.,Meyer Mojzes, Melinda,Schenk, Kurt,Renaud, Philippe
, p. 12318 - 12327 (2017/12/08)
A simple procedure for the conversion of tertiary lactams to 2-monoalkylated cyclic amines is described. The reaction sequence involves conversion of a lactam to a thioiminium ion followed by reaction with an organocopper (RCu) reagent and final reduction with triacetoxyborohydride. The reaction is high yielding and shows an excellent functional group tolerance. Its utility is demonstrated by a rapid synthesis of indolizidine 167B. The excellent chemoselectivity of the process, where only monoalkylation products are formed, is rationalized by a mechanism involving the formation of a transient enamine.
An efficient method to convert lactams and amides into 2,2-dialkylated amines
Agosti, Alessandro,Britto, Sebastian,Renaud, Philippe
supporting information; experimental part, p. 1417 - 1420 (2009/04/12)
(Chemical Equation Presented) A practical method for the synthesis of gem-2,2-disubstituted tertiary amines from the corresponding lactams (or amides) is reported. It is based on the reaction of thioiminium ions, easily prepared from lactams and amides wi
