179178-67-7Relevant articles and documents
5-pyrrolyl-6-halogeno-2-pyridylmethylsulfinyl benzimidazole derivatives
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, (2008/06/13)
The present invention relates to a novel compound 5-pyrrolyl-6-halogeno-2-pyridylmethylsulfinylbenzimidazole derivative having the following formula (I): STR1 or a pharmaceutically acceptable salt thereof, in which X represents S, SO or SO2, Y represents halogen, R1 and R2 independently from each other represent hydrogen or methyl, R3 represents hydrogen, C1 -C8 alkyl, --SR6, --N(R7)2, or a group of formula --OR6 or --O(CH2)m --Z, wherein R6 represents C1 -C4 alkyl, C2 -C4 alkenyl, C3 -C10 cycloalkyl optionally substituted with C1 -C4 alkyl, C2 -C5 fluoroalkyl, phenyl optionally substituted with C1 -C4 alkyl or benzyl optionally substituted with C1 -C4 alkyl, R7 represents hydrogen or C1 -C5 alkyl, Z represents a group of formula --O(CH2)q --R9 wherein q denotes an integer of 1 to 3, and R9 represents hydrogen, m represents an integer of 2 to 10, and