179474-79-4 Usage
Description
1-(3-Methoxypropyl)-4-piperidinamine is an organic compound that serves as a crucial synthetic intermediate in the pharmaceutical industry. It is characterized by its unique chemical structure, which includes a piperidine ring and a methoxypropyl group, making it a versatile building block for the development of various medications.
Uses
Used in Pharmaceutical Industry:
1-(3-Methoxypropyl)-4-piperidinamine is used as a synthetic intermediate for the development of Prucalopride Succinate (P838950), a selective 5-HT4 receptor agonist. 1-(3-Methoxypropyl)-4-piperidinamine is particularly effective in treating chronic constipation and has been approved for use in Europe. Its role in the synthesis of Prucalopride highlights its importance in addressing gastrointestinal disorders and improving patients' quality of life.
While the provided materials do not mention additional applications in different industries, the compound's unique structure suggests that it may have potential uses in other areas, such as chemical research or material science. However, without further information, it is not possible to list specific applications in other industries.
Check Digit Verification of cas no
The CAS Registry Mumber 179474-79-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,4,7 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 179474-79:
(8*1)+(7*7)+(6*9)+(5*4)+(4*7)+(3*4)+(2*7)+(1*9)=194
194 % 10 = 4
So 179474-79-4 is a valid CAS Registry Number.
179474-79-4Relevant articles and documents
A process for preparing 1 - (3 - a oxygen propyl) piperidine - 4 - amine (by machine translation)
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Paragraph 0017; 0020; 0023; 0024; 0028; 0029, (2017/08/26)
The invention discloses a method for preparing 1-(3-methoxypropyl)-4-piperidinamine. The method includes the following steps: the raw material, namely 4-aminopiperdine is adopted, primary amine is selectively protected by benzophenone based on the difference of chemical properties of primary amine and secondary amine, free secondary amine is subjected to proton abstraction, then the free secondary amine subjected to proton abstraction reacts with 3-methoxy-bromopropane, under the acid condition, the protecting group is removed, and finally, the product is obtained. The synthetic process is simple to operate, besides, the removed protecting group subjected to simple treatment can be recycled, and industrial enlarged production is facilitated.