1795-83-1Relevant articles and documents
The Solvolysis of N-Acetoxy-2-acetylaminofluorene and N-Acetoxy-4-acetylaminobiphenyl: Delicate Balance between Nitrenium Ion Formation and Hydrolysis
Underwood, Graham R.,Kirsch, Robert B.
, p. 136 - 138 (1985)
The solvolysis of N-acetoxy-2-acetylaminofluorene in aqueous acetone at neutral pH proceeds exclusively with nitrenium ion formation while under the same conditions, the 4-aminobiphenyl analogue undergoes exclusive acyl-oxygen scission.
Enzymatic and mechanistic studies on the formation of N- phenylglycolohydroxamic acid from nitrosobenzene and pyruvate in spinach leaf homogenate
Tatsunami, Ryosuke,Yoshioka, Tadao
, p. 590 - 596 (2006)
The biotransformation mechanism of an unknown metabolite formed enzymatically from nitrosobenzene (NOB) and pyruvate in spinach (Spinacea oleracea L.) was investigated using spinach leaf homogenate. The unknown metabolite was identified as N-phenylglycolo
Catalyst-free generation of acyl radicals induced by visible light in water to construct C-N bonds
Ran, Maogang,He, Jiaxin,Yan, Boyu,Liu, Wenbo,Li, Yi,Fu, Yunfen,Li, Chao-Jun,Yao, Qiuli
supporting information, p. 1970 - 1975 (2021/03/16)
We describe herein a catalyst-free and redox-neutral photochemical strategy for the direct generation of acyl radicals from α-diketones, and its selective conversion of nitrosoarenes to hydroxyamides or amides with AcOH or NaCl as an additive. The reaction was carried out under mild conditions in water with purple LEDs as the light source. A broad scope of substrates was demonstrated. Mechanistic experiments indicate that α-diketones cleave to give acyl radicals, with hydroxyamides being further reduced to amides.
Synthesis method of N-acylhydroxylamine
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Paragraph 0020-0040; 0062-0076, (2020/09/30)
The invention relates to a synthesis method of N-acylhydroxylamine, which comprises the following steps: starting from o-diketone and a nitroso compound, and adding an acid thereby efficiently obtaining the structure of N-acylhydroxylamine under the irradiation of visible light or ultraviolet light, wherein a part of the obtained product is an important biomedical chemical intermediate. Accordingto the method, the o-diketone and the nitroso compound which are cheap and easy to obtain are used as raw materials, only visible light or ultraviolet light irradiation is needed, cheap acid is addedin the reaction process, a catalyst or a metal compound is not needed, and only water can be used as a solvent in mass production. The whole production process is environmentally friendly, economical,efficient and low in cost, and has very remarkable advantages compared with the conventional production process.
