181697-05-2Relevant articles and documents
Method for preparing Parecoxib
-
Paragraph 0016; 0017; 0018, (2016/12/26)
The invention relates to a method for preparing Parecoxib, and belongs to the synthesis field of pharmaceutical chemistry. 1,2-diphenyl-ethanone is used as an starting raw material, a reaction is carried out between the starting raw material and chlorosul
Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof
-
Page/Page column 24, (2010/02/06)
The present invention relates to sulfonyl-containing 2,3-diarylindole, especially to new compounds of general Formula, to a preparation method for their preparation, to pharmaceutical compositions containing said compound, and to the medical use thereof in the treatment of diseases relating to the inhibition of cyclooxygenase-2 (COX-2).
Substituted imidazo 1,2a}azines as selective inhibitors of cox-2
-
Page column 17, (2010/11/30)
The invention refers to new compounds of formula (I), wherein A and B are selected from the group consisting of N and CH, with the condition that when A is N, B is N; R1is selected from the group consisting of CH3and NH2;