1826-18-2

Basic information

• Product Name: Thiazole, 5-methyl-4-phenyl-
• Synonyms: Thiazole, 5-methyl-4-phenyl-;5-Methyl-4-phenylthiazole
• CAS NO: 1826-18-2
• Molecular Formula: C₁₀H₉NS
• Molecular Weight: 175.25
• Mol File: 1826-18-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Thiazole, 5-methyl-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiazole, 5-methyl-4-phenyl-(1826-18-2)
• EPA Substance Registry System: Thiazole, 5-methyl-4-phenyl-(1826-18-2)

Safety Data

• Hazardous Substances Data: 1826-18-2(Hazardous Substances Data)

Usage

General Description

Thiazole, 5-methyl-4-phenyl- is a chemical compound consisting of a thiazole ring with a methyl group and a phenyl group substituent. It is a heterocyclic aromatic compound that is commonly used in the pharmaceutical industry for the synthesis of various drugs. Thiazole, 5-methyl-4-phenyl- has been found to possess a range of biological activities, including antimicrobial, antiviral, and anticancer properties. It is also used as an intermediate in the production of dyes, pigments, and other organic compounds. Additionally, this chemical compound has been studied for its potential role in the treatment of neurological disorders and as a building block for the development of new drugs with specific therapeutic benefits.

Upstream product

• 123971-43-7 C₁₁H₉NO₂S 
• 159670-43-6 C₁₃H₁₃NO₂S 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 50-00-0 formaldehyd 
• 115-08-2 thiocarboxamide 
• 77287-34-4 formamide 

Downstream Products

• 25020-80-8 1,3-bis-[4-(5-methyl-thiazol-4-yl)-phenyl]-thiourea 
• 7021-85-4 1-[4-(5-methyl-thiazol-4-yl)-phenyl]-3-(4-pentyloxy-phenyl)-thiourea 
• 7021-93-4 1-(4-butoxy-phenyl)-3-[4-(5-methyl-thiazol-4-yl)-phenyl]-thiourea 
• 7021-94-5 1-(4-isobutoxy-phenyl)-3-[4-(5-methyl-thiazol-4-yl)-phenyl]-thiourea 
• 7021-91-2 1-[4-(5-methyl-thiazol-4-yl)-phenyl]-3-(4-propoxy-phenyl)-thiourea 
• 7021-92-3 1-(4-isopropoxy-phenyl)-3-[4-(5-methyl-thiazol-4-yl)-phenyl]-thiourea 
• 7091-90-9 1-(4-ethoxy-phenyl)-3-[4-(5-methyl-thiazol-4-yl)-phenyl]-thiourea 
• 7021-90-1 1-(4-methoxy-phenyl)-3-[4-(5-methyl-thiazol-4-yl)-phenyl]-thiourea 
• 25021-54-9 4-(5-methyl-thiazol-4-yl)-aniline 
• 78502-90-6 4-Phenyl-5-thiazolyl-methyl(triphenyl)phosphoniumbromid 
• 78520-04-4 5-Brommethyl-4-phenylthiazol 
• 25021-45-8 5-methyl-4-(4-nitro-phenyl)-thiazole 

Relevant articles and documents

Novel series of 3-amino-N-(4-aryl-1,1-dioxothian-4-yl)butanamides as potent and selective dipeptidyl peptidase IV inhibitors

A series of novel 3-amino-N-(4-aryl-1,1-dioxothian-4-yl)butanamides were investigated as dipeptidyl peptidase IV (DPP-4) inhibitors. Introduction of a 4-phenylthiazol-2-yl group showed highly potent DPP-4 inhibitory activity. Among various derivatives, (3R)-3-amino-N-(4-(4-phenylthiazol-2-yl)-tetrahydro-2H- thiopyran-4-yl)-4-(2,4,5-trifluorophenyl)butanamide 1,1-dioxide (30) reduced blood glucose excursion in an oral glucose tolerance test by oral administration.