184370-65-8Relevant articles and documents
N -Alkynyl Pyrrole Based Total Synthesis of Shensongine A
Kerwin, Sean M.,Reinus, Brandon J.
, p. 4085 - 4105 (2019/10/28)
A copper-catalyzed N-alkynylation of pyrrole and a gold-catalyzed spiroketalization were key steps in the total synthesis of the pyrrole spiroketal alkaloid shensongine A. The preparation of this alkaloid is concise and amenable to the rapid synthesis of
Efficient synthesis of monosubstituted 3-alkynylfurans via Suzuki coupling
Yang, Xiaobao,Zhu, Li,Zhou, Yuedong,Li, Zhong,Zhai, Hongbin
, p. 1729 - 1732 (2008/12/22)
A convenient synthesis of monosubstituted 3-alkynyl-furans by Suzuki coupling reaction of 3-furanylboronic acid with substituted acetylene bromides is described. The internal alkyne products were attainable in 50-89% yields from substrates free of relatively acidic protons. Our protocol is expected to find applications in the synthesis of structurally related natural products.