185522-67-2Relevant articles and documents
Asymmetric 1,3-Dipolar Cycloaddition: Synthesis of N-protected (4S)-4-Hydroxy L-Glutamic Acid Diester
Gefflaut, Thierry,Bauer, Udo,Airola, Karri,Koskinen, Ari M. P.
, p. 3099 - 3102 (2007/10/03)
An asymmetric synthesis of N-protected (4S)-4-hydroxy L-glutamic acid diester is described.The key feature of the synthesis is the asymmetric 1,3-dipolar cycloaddition of nitrone 4 with 5, which provides stereoselectively the isoxazolidine with the correc