1865-13-0

Basic information

• Product Name: 2-Propenoic acid, 3-(phenylsulfonyl)-, methyl ester, (2E)-
• CAS NO: 1865-13-0
• Molecular Formula: C10H10O4S
• Molecular Weight: 226.253
• Mol File: 1865-13-0.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(phenylsulfonyl)-, methyl ester, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(phenylsulfonyl)-, methyl ester, (2E)-(1865-13-0)
• EPA Substance Registry System: 2-Propenoic acid, 3-(phenylsulfonyl)-, methyl ester, (2E)-(1865-13-0)

Safety Data

• Hazardous Substances Data: 1865-13-0(Hazardous Substances Data)

Upstream product

• 1729-67-5 Methyl 2,3-dibromopropionate 
• 873-55-2 sodium benzenesulfonate 
• 19169-90-5 bromomethylphenylsulfone 
• 96-32-2 bromoacetic acid methyl ester 
• 922-67-8 propynoic acid methyl ester 
• 108-98-5 thiophenol 
• 108-31-6 maleic anhydride 
• 91158-50-8 (cycloocta-1,5-diene)(methyl trans-β-(phenylsulfonyl)acrylate)nickel 
• 711-29-5 3-phenylsulfonyl-2(Z)-propenoic acid 
• 22198-59-0 methyl 3-phenylthiopropanoate 
• 7205-98-3 chloromethyl phenyl sulfone 
• 69627-35-6 N,N'-bis(benzenesulfonyl)-o-phenylenediamide 
• 55543-78-7 (+/-)-Methyl 3-(Phenylsulfinyl)propanoate 
• 82101-75-5 (Z)-ethyl 3-(tributylstannyl)acrylate 

Downstream Products

• 132371-02-9 dimethyl 3-benzenesulphonyl-2-pyrrolidinomethylidinylglutarate 
• 7424-91-1 methyl 3,3-dimethoxypropionate 
• 1590379-43-3 methyl (2S,3R,4R)-4-(phenylsulfonyl)-2-(2-pyridinyl)pyrrolidine-3-carboxylate 
• 1590379-45-5 methyl (2S,3R,4R)-2-(5-bromopyridin-2-yl)-4-(phenylsulfonyl)pyrrolidine-3-carboxylate 
• 1402841-61-5 (2R,3R,4S)-2-ethyl-3-methyl 2-phenethyl-4-(phenylsulfonyl)pyrrolidine-2,3-dicarboxylate 
• 1402841-62-6 (2R,3R,4S)-dimethyl 2-methyl-4-(phenylsulfonyl)pyrrolidine-2,3-dicarboxylate 
• 1402841-64-8 (3S,4R,5S)-methyl 9,9-dimethyl-6-oxo-3-(phenylsulfonyl)-7-oxa-1-azaspiro[4.4]nonane-4-carboxylate 
• 1402841-60-4 (2R,3R,4S)-2-ethyl-3-methyl 2-methyl-4-(phenylsulfonyl)pyrrolidine-2,3-dicarboxylate 
• 1352713-27-9 (2R,3R,4S,5R)-dimethyl 3-(phenylsulfonyl)-5-p-tolylpyrrolidine-2,4-dicarboxylate 
• 1352713-38-2 C₂₄H₂₉NO₆S 
• 1352713-30-4 (2R,3R,4S,5R)-dimethyl 5-(4-methoxyphenyl)-3-(phenylsulfonyl)pyrrolidine-2,4-dicarboxylate 
• 1352713-25-7 (2R,3R,4S,5R)-dimethyl 5-(2-chlorophenyl)-3-(phenylsulfonyl)pyrrolidine-2,4-dicarboxylate 
• 1352713-31-5 (2R,3R,4S,5R)-dimethyl 5-(naphthalen-2-yl)-3-(phenylsulfonyl)pyrrolidine-2,4-dicarboxylate 

Relevant articles and documents

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Chemoselective synthesis of unsymmetrical internal alkynes or vinyl sulfones via palladium-catalyzed cross-coupling reaction of sodium sulfinates with alkynes

A highly efficient and mild palladium-catalyzed cross-coupling of sodium sulfinates and alkynes for the selective synthesis of unsymmetrical internal alkynes and vinyl sulfones has been developed. This methodology has advantages of easily accessible starting materials, functional group tolerance and a wide range of substrates, which provides rapid access to alkynes and vinyl sulfones.

The phenylsulfonyl group as a temporal regiochemical controller in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides

(Chemical Equation Presented) Controlling the regioselectivity: The phenylsulfonyl group controlled the regioselectivity in the title reaction to afford pyrrolidine-2,3-dicarboxylates with good regioselectivity and high exo selectivity and enantioselectivity (see scheme). The products are precursors to substituted pyrrolidines and pyrrolines that are not attainable by direct 1,3-dipolar cycloadditions with typical acrylates.