1886-52-8

Basic information

• Product Name: NSC51271
• Synonyms: NSC51271;Ethyl 2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enoate, Ethyl alpha-cyano-4-(dimethylamino)cinnamate
• CAS NO: 1886-52-8
• Molecular Formula: C₁₄H₁₆N₂O₂
• Molecular Weight: 244.28904
• Mol File: 1886-52-8.mol
• Article Data: 69

Chemical Properties

• Boiling Point: 402.4°Cat760mmHg
• Flash Point: 197.2°C
• Appearance: /
• Density: 1.138g/cm³
• Vapor Pressure: 1.1E-06mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: NSC51271(CAS DataBase Reference)
• NIST Chemistry Reference: NSC51271(1886-52-8)
• EPA Substance Registry System: NSC51271(1886-52-8)

Safety Data

• Hazardous Substances Data: 1886-52-8(Hazardous Substances Data)

Usage

Description

NSC51271, also known as 3-(3,4-dihydroxyphenyl)propanoic acid, is a chemical compound derived from the amino acid tyrosine and found in plants like Tinospora cordifolia. It has been studied for its antioxidant and anti-inflammatory properties, which may contribute to overall health and the prevention of chronic diseases.

Uses

Used in Pharmaceutical Industry:
NSC51271 is used as a potential therapeutic agent for various conditions due to its antioxidant and anti-inflammatory properties. It is being studied for its potential effects in treating diabetes, cardiovascular disease, and neurodegenerative disorders.
Used in Health and Wellness Applications:
NSC51271 is used as a health supplement to promote overall well-being and prevent chronic diseases, thanks to its beneficial antioxidant and anti-inflammatory properties. Further research is needed to fully understand the potential uses and mechanisms of action of NSC51271 in the body.

InChI:InChI=1/C14H16N2O2/c1-4-18-14(17)12(10-15)9-11-5-7-13(8-6-11)16(2)3/h5-9H,4H2,1-3H3/b12-9-

Upstream product

• 57806-78-7 p-dimethylamino-1-(dichloromethyl)benzene 
• 105-56-6 ethyl 2-cyanoacetate 
• 889-37-2 N,N-dimethyl-4-((phenylimino)methyl)aniline 
• 64-17-5 ethanol 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 107-91-5 cyanoacetic acid amide 
• 2826-28-0 p-(N-dimethylamino benzylidene) malononitrile 
• 14447-18-8 benzyl 2-cyanoacetate 
• 877-79-2 4-(dimethylamino)-N-methylbenzylimine 
• 1187-46-8 ethyl bromocyanoacetate 
• 154180-94-6 [1-(4-Dimethylamino-phenyl)-meth-(E)-ylidene]-(5-methyl-2H-pyrazol-3-yl)-amine 
• 62309-98-2 Chlormethylen-cyanessigsaeure-ethylester 
• 121-69-7 N,N-dimethyl-aniline 

Downstream Products

• 857814-57-4 2-aminomethyl-3-(4-dimethylamino-phenyl)-propionic acid 
• 112906-24-8 2-[(Z)-3-(4-Dimethylamino-phenyl)-1-thiophen-2-yl-allylidene]-malononitrile 
• 1442466-74-1 6-cyano-5,6-dihydro-7-(4-dimethylaminophenyl)-5-oxo-[1,3,4]thiadiazolo[3,2-a]-pyrimidine-2-sulfonamide 
• 77145-76-7 (Z)-4-(dimethylamino)benzaldehyde oxime 

Relevant articles and documents

Bismuth (III) Triflate: A Mild, Efficient Promoter for the Synthesis of Trisubstituted Alkenes through Knoevenagel Condensation

In this work, smooth efficient and eco-friendly two component coupling method is reported for the synthesis of Knoevenagel Condensation product in presence of Bi(OTf)3 catalyst under solvent free condition. Catalyst has participated in condensation between substituted aldehydes (aromatic and hetero-aromatic) and active methylene compounds (ethyl cyanoacetate, malononitrile and cyanoacetamide) effectively to generate an excellent yield of the product. Bi(OTf)3 catalyst is stable, inexpensive and easily available was used for four times in this reaction without loss of catalytic activity. [Formula Presented]

Prolinamide functionalized polyacrylonitrile fiber with tunable linker length and surface microenvironment as efficient catalyst for Knoevenagel condensation and related multicomponent tandem reactions

A series of new prolinamide polyacrylonitrile fiber catalysts with tunable length of alkyl linker and different linker group were prepared by covalent bonding for the first time and well characterized by mechanical strength, FT-IR, XRD, EA, TGA, SEM and water contact angel. The catalytic activities of these fiber catalysts were evaluated in Knoevenagel condensation and one-pot Knoevenagel-Michael multicomponent tandem reactions to synthesize α, β-unsaturated nitrile and 2-amino-4H-chromene derivatives in water. The result show that the suitable linker length attaching amines to fiber matrix as well as the constructed hydrophobic microenvironment by linker group within the surface layers of fiber materials effectively promotes the reactions. In addition, the good swollen capacity of fiber in solvent ensure that the reaction proceed well. Fiber catalyst PANPA?2F modified by prolinamide with a C2 alkyl chain exhibited the best catalytic performance and can be easily recovered and reused for at least ten consecutive cycles without significant loss of catalytic activity and active sites leaching.

BLUE LIGHT BLOCKLING SYSTEM CONTAINING PYRAZOLINE OR/AND BENZOIC ACID COMPOUNDS

The present invention relates to an blue light blocking system characterized in that the blue light blocking agents possess the structure of a pyrazoline of the formula (I) or/and a phenylacrylic acid of the formula (II). The compounds of formula (I) or / and formula (II) fully cover the range of short-wavelength blue light to protect eyes; it can also selectively absorb long-wavelength blue light, so that the transmitted light can provide a particularly good visual experience to humans. The invention is applicable to products such as optical films, optical lenses, goggles, skin care, lighting devices, paints, adhesives, or panels. These products have a light-colored appearance and the penetrating light provides an excellent visual experience for humans.