192124-66-6 Usage
Description
N-BOC-N-[3-(BOC-AMINO)PROPYL]GLYCINE is a chemical compound that serves as a protecting group in organic synthesis, particularly in peptide synthesis. It is a glycine molecule with a N-BOC (tert-butoxycarbonyl) protecting group attached to the nitrogen atom, and it also features a 3-(BOC-amino)propyl group. This structural element can be utilized for linking to other molecules or for altering the reactivity of the glycine moiety. N-BOC-N-[3-(BOC-AMINO)PROPYL]GLYCINE's design allows for selective reactions to take place at other functional groups within the molecule, while the amine group of glycine remains protected.
Uses
Used in Pharmaceutical Industry:
N-BOC-N-[3-(BOC-AMINO)PROPYL]GLYCINE is used as a protecting group in the synthesis of peptides for various pharmaceutical applications. Its role is crucial in protecting the amine group of glycine, enabling selective reactions at other sites within the peptide chain. This selective protection is vital for the successful synthesis of complex peptide structures, which can be used in the development of new drugs and therapies.
Used in Research and Development:
In the field of research and development, N-BOC-N-[3-(BOC-AMINO)PROPYL]GLYCINE is utilized for the synthesis and modification of peptides and other biomolecules. Its ability to protect the amine group of glycine allows researchers to explore novel chemical reactions and create new molecular structures with potential applications in various scientific and medical fields.
Used in Chemical Synthesis:
N-BOC-N-[3-(BOC-AMINO)PROPYL]GLYCINE is also used in general chemical synthesis as a protecting group for the amine function. This allows chemists to carry out reactions on other parts of the molecule without affecting the amine group, which can be crucial for the synthesis of complex organic compounds and the development of new materials.
Check Digit Verification of cas no
The CAS Registry Mumber 192124-66-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,2,1,2 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 192124-66:
(8*1)+(7*9)+(6*2)+(5*1)+(4*2)+(3*4)+(2*6)+(1*6)=126
126 % 10 = 6
So 192124-66-6 is a valid CAS Registry Number.
InChI:InChI=1/C15H28N2O6/c1-14(2,3)22-12(20)16-8-7-9-17(10-11(18)19)13(21)23-15(4,5)6/h7-10H2,1-6H3,(H,16,20)(H,18,19)
192124-66-6Relevant articles and documents
Chiral recognition by CD-sensitive dimeric zinc porphyrin host. 1. Chiroptical protocol for absolute configurational assignments of monoalcohols and primary monoamines
Kurtan,Nesnas,Li,Huang,Nakanishi,Berova
, p. 5962 - 5973 (2007/10/03)
A general microscale protocol for the determination of absolute configurations of primary amino groups or secondary hydroxyl groups linked to a single stereogenic center is described. The chiral substrates are linked to the achiral trifunctional bidentate carrier molecule (3-aminopropylamino)acetic acid (1, H2NCH2CH2CH2NHCH2COOH) and the resultant conjugates are then complexed with dimeric zinc porphyrin host 2 giving rise to 1:1 host/guest sandwiched complexes. These complexes exhibit exciton-coupled bisignate CD spectra due to stereodifferentiation leading to preferred porphyrin helicity. Since the chiral sense of twist between the two porphyrins in the complex is dictated by the stereogenic center of the substrate, the sign of the couplet determines the absolute configuration at this center. The twist of the porphyrin tweezer in the complex can be predicted from the relative steric sizes of the groups flanking the stereogenic center, such that the bulkier group protrudes from the complex sandwich. In certain α-hydroxy esters and α-amino esters, electronic factors and hydrogen bonding govern the preferred conformation of the complex, and hence the CD spectra.
