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19499-60-6

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19499-60-6 Usage

General Description

N-Methyl-N-(4-nitrobenzyl)amine hydrochloride is a chemical compound with the formula C8H10ClN2O2. It is a white to off-white crystalline solid that is soluble in water and organic solvents. N-METHYL-N-(4-NITROBENZYL)AMINE HYDROCHLORIDE is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and organic materials. It is also used as a reagent in organic synthesis, particularly in the preparation of amine and amide derivatives. Additionally, it has applications in the production of dyes, pigments, and other specialty chemicals. This chemical compound should be handled with care, as it may be harmful if ingested, inhaled, or absorbed through the skin, and proper safety precautions should be taken when working with it.

Check Digit Verification of cas no

The CAS Registry Mumber 19499-60-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,4,9 and 9 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 19499-60:
(7*1)+(6*9)+(5*4)+(4*9)+(3*9)+(2*6)+(1*0)=156
156 % 10 = 6
So 19499-60-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O2.ClH/c1-9-6-7-2-4-8(5-3-7)10(11)12;/h2-5,9H,6H2,1H3;1H

19499-60-6Relevant articles and documents

Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent

Chen, I-Chung,Chen, Mei-Chuan,Hsieh, Chien-Ming,Hsu, Kai-Cheng,Lai, Row-Wen,Lin, Tony Eight,Liou, Jing-Ping,Nepali, Kunal,Ojha, Ritu,Pan, Shiow-Lin

, p. 17824 - 17845 (2022/01/03)

Pragmatic insertion of pargyline, a LSD1 inhibitor, as a surface recognition part in the HDAC inhibitory pharmacophore was planned in pursuit of furnishing potent antiprostate cancer agents. Resultantly, compound 14 elicited magnificent cell growth inhibi

Epoxide-Mediated Stevens Rearrangements of α-Amino-Acid-Derived Tertiary Allylic, Propargylic, and Benzylic Amines: Convenient Access to Polysubstituted Morpholin-2-ones

Jin, You-Xiang,Yu, Bang-Kui,Qin, Si-Ping,Tian, Shi-Kai

supporting information, p. 5169 - 5172 (2019/03/28)

A new strategy has been established for the synthesis of polysubstituted morpholin-2-ones through Stevens rearrangements of tertiary amines via in situ activation with epoxides. A range of α-amino acid-derived tertiary allylic, propargylic, and benzylic amines reacted with epoxides in the presence of zinc halide catalysts to afford structurally diverse allyl-, allenyl-, and benzyl-substituted morpholin-2-ones, respectively, in moderate-to-good yields with high regioselectivity. The process involves [2,3]- and [1,2]-Stevens rearrangements of quaternary ammonium ylide intermediates and constitutes a very convenient method to prepare polysubstituted morpholin-2-ones through tandem formation of C?N, C?O, and C?C bonds. Moreover, replacing epoxides with aziridines permitted the synthesis of polysubstituted piperazin-2-ones.

Novel chiral bis-phosphoramides as organocatalysts for tetrachlorosilane-mediated reactions

Rossi, Sergio,Ziliani, Marco,Annunziata, Rita,Benaglia, Maurizio

supporting information, (2018/01/12)

The formation of novel chiral bidentate phosphoroamides structures able to promote Lewis base-catalyzed Lewis acid-mediated reactions was investigated. Two different classes of phosphoroamides were synthetized: the first class presents a phthalic acid/pri

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