19714-18-2

Basic information

• Product Name: C₁₄H₁₀N₂O₂
• CAS NO: 19714-18-2
• Molecular Weight: 238.246
• Mol File: 19714-18-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₀N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₀N₂O₂(19714-18-2)
• EPA Substance Registry System: C₁₄H₁₀N₂O₂(19714-18-2)

Safety Data

• Hazardous Substances Data: 19714-18-2(Hazardous Substances Data)

Upstream product

• 91-56-5 indole-2,3-dione 
• 100-65-2 N-Phenylhydroxylamine 
• 22942-87-6 3-bromo-1,3-dihydro-2H-indol-2-one 
• 586-96-9 Nitrosobenzene 
• 22755-09-5 N-phenyl hydroxylamine hydrochloride 
• 33828-98-7 3-phenylimino-2-indolinone 
• 62-53-3 aniline 
• 607-28-3 (E)-1H-indole-2,3-dione 3-oxime 
• 98-80-6 phenylboronic acid 
• 607-28-3 3-(hydroxyimino)indolin-2-one 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 3265-29-0 3-diazo-indolin-2-one 
• 612-54-4 2-chloro-3H-indol-3-one 

Downstream Products

• 91-56-5 indole-2,3-dione 
• 495-48-7 azoxybenzene 
• 1407968-18-6 C₂₁H₂₀N₂O₆ 
• 1407968-32-4 C₂₁H₂₀N₂O₆ 
• 603-23-6 3-phenyl-2,4-(1H,3H)-quinazolinedione 
• 76369-72-7 C₁₈H₁₈N₂O₃ 
• 58418-26-1 2-phenylimino-4H-benzo[1,4]oxazin-3-one 

Relevant articles and documents

Antiproliferative activity of novel isatinyl/indanyl nitrones (INs) as potential spin trapping agents of free radical intermediates

A series of ketonitrones derived from isatin and indanone (INs) were synthesized and evaluated for their antiproliferative activities against several human cancer cell lines. Then, the antioxidant properties of these substrates were measured by the DPPH test to report their biological activity in terms of their spin trapping action. In particular, one substrate has showed very high biological and scavenging activity, probably due to the strong correlation between its spin trapping activity and structure.

Single-Step Approach toward Nitrones via Pyridinium Ylides: The DMAP-Catalyzed Reaction of Benzyl Halides with Nitrosoarenes

A single-step approach is reported for the preparation of nitrones from benzyl halides and nitrosoarenes via pyridinium ylides, utilizing 4-dimethylaminopyridine (DMAP) catalyst and mild reaction conditions (Li2CO3, dimethylacetamide, and room temperature). The reaction provides both keto-and aldonitrones in high yields with a wide scope for benzyl halides and nitrosoarenes. In the same reaction system, 2-methyl-2-nitrosopropane, which does not have an aryl group, also affords the corresponding N-tert-butyl nitrones from primary benzyl bromides that have an electron-withdrawing group. As an application of the reaction, methyl 2-bromo-2-phenylacetate was used to prepare the corresponding isoxazolidine by a sequential one-pot synthesis.

Synthesis and Evaluation of Novel Spiro[oxindole-isoxazolidine] Derivatives as Potent Antioxidants

The antioxidant activity of isatin derivatives can be described with the presence of enolic hydroxyl group at the second position of the ring because of the keto-enol tautomerism between NH and C O groups of indolone moiety. The reducing ability of the tested compounds was evaluated by their interaction with the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) at various concentrations. Novel spiro[oxindole-isoxazolidine] derivatives (4a, 4b, 4c, 4d, 4e, 4f, 4g, 4h, 4i) have been synthesized by 1,3-dipolar cycloaddition reactions of variously substituted maleimides (1) with isatin ketonitrone (3) and tested for their in vitro antioxidant potency in the DPPH assay. All the synthesized compounds have been identified as potent in vitro antioxidants.