19714-73-9

Basic information

• Product Name: Benzene, 1-cyclopropyl-3-Methyl-
• Synonyms: Benzene, 1-cyclopropyl-3-Methyl-
• CAS NO: 19714-73-9
• Molecular Formula: C₁₀H₁₂
• Molecular Weight: 132.20228
• Mol File: 19714-73-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 198.2°C at 760 mmHg
• Flash Point: 64.3°C
• Appearance: /
• Density: 0.988g/cm³
• Vapor Pressure: 0.513mmHg at 25°C
• Refractive Index: 1.558
• CAS DataBase Reference: Benzene, 1-cyclopropyl-3-Methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-cyclopropyl-3-Methyl-(19714-73-9)
• EPA Substance Registry System: Benzene, 1-cyclopropyl-3-Methyl-(19714-73-9)

Safety Data

• Hazardous Substances Data: 19714-73-9(Hazardous Substances Data)

Usage

General Description

Benzene, 1-cyclopropyl-3-methyl is a chemical compound with the molecular formula C10H12. It is a derivative of benzene with a cyclopropyl group and a methyl group attached to the benzene ring. Benzene, 1-cyclopropyl-3-methyl- is commonly used as an intermediate in the synthesis of various organic chemicals and pharmaceuticals. It is also used as a building block for the production of agrochemicals and specialty chemicals. Benzene, 1-cyclopropyl-3-methyl has potential applications in the field of medicine and drug discovery due to its unique chemical structure and properties. However, it is important to handle this compound with caution, as it has been associated with adverse health effects and is considered a hazardous substance.

InChI:InChI=1/C10H12/c1-8-3-2-4-10(7-8)9-5-6-9/h2-4,7,9H,5-6H2,1H3

Upstream product

• 100-80-1 3-methylstyrene 
• 67-66-3 chloroform 
• 75-11-6 diiodomethane 
• 591-17-3 meta-bromotoluene 
• 106-96-7 propargyl bromide 
• 411235-57-9 cyclopropylboronic acid 
• 19714-75-1 1,3-Dibrom-1-(m-tolyl)-propan 
• 6746-94-7 Cyclopropylacetylene 
• 78-79-5 isoprene 
• 58824-47-8 1-(m-tolyl)prop-2-en-1-ol 
• 873-49-4 cyclopropylbenzene 
• 74-88-4 methyl iodide 
• 23719-80-4 cyclopropylmagnesium bromide 

Downstream Products

• 1124-20-5 2-(3-methylphenyl)propene 
• 51699-43-5 1-(3-methylphenyl)-1,3-propanediol 

Relevant articles and documents

Regioselective Metalation of Phenylcyclopropane and Smooth Addition of 1-Phenylcyclopropyl Potassium onto Ethylene

Whereas pentyl sodium in pentane mainly promotes a hydrogen/metal exchange reaction at the m- and p-position of phenylcyclopropane, both the butyllithium/potassium t-butoxide reagent and trimethylsilylmethyl potassium in tetrahydrofuran convert phenylcyclopropane exclusively into 1-phenylcyclopropyl potassium.The latter organometallic derivative adds smoothly onto the double bond of ethylene at temperatures around -40 deg.

Lewis Base-Promoted Ring-Opening 1,3-Dioxygenation of Unactivated Cyclopropanes Using a Hypervalent Iodine Reagent

A facile and effective system has been developed for the regio- and chemoselective ring-opening/electrophilic functionalization of cyclopropanes through C?C bond activation by [bis(trifluoroacetoxy)iodo]benzene with the aid of the Lewis basic promoter p-toluenesulfonamide. The p-toluenesulfonamide-promoted system works well for a wide range of cyclopropanes, resulting in the formation of 1,3-diol products in good yields and regioselectivity.

IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS

A process of converting a carbon-carbon multiple bond to a cyclopropane ring, comprising the addition of a N-alkyl-N-nitroso compound to a mixture of alkene precursor, aqueous base and Pd(II)-catalyst, with the N-alkyl-N-nitroso compound obtained directly from an alkyl amine derivative, NaNO2 and an acid via phase separation of the N-alkyl-N-nitroso compound from the aqueous phase.