19803-10-2

Basic information

• Product Name: 2-(4-methoxyphenyl)-5-methylbenzo[b]furan
• Synonyms: 2-(4-methoxyphenyl)-5-methylbenzo[b]furan
• CAS NO: 19803-10-2
• Molecular Weight: 238.286
• Mol File: 19803-10-2.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxyphenyl)-5-methylbenzo[b]furan(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)-5-methylbenzo[b]furan(19803-10-2)
• EPA Substance Registry System: 2-(4-methoxyphenyl)-5-methylbenzo[b]furan(19803-10-2)

Safety Data

• Hazardous Substances Data: 19803-10-2(Hazardous Substances Data)

Upstream product

• 16188-57-1 2-iodo-4-methylphenol 
• 84384-30-5 4-(4-methoxyphenyl)-2-methyl-3-butyn-2-ol 
• 5720-07-0 4-methoxyphenylboronic acid 
• 123389-03-7 (E)-1-(1,2-dichlorovinyloxy)-4-methylbenzene 
• 1313886-73-5 2-((4-methoxyphenyl)ethynyl)-4-methylphenyl acetate 
• 106-44-5 p-cresol 
• 6627-55-0 2-bromo-p-cresol 
• 768-60-5 4-methoxyphenylacetylen 
• 1452849-98-7 5-methyl-2-hydroxybenzyltriphenylphosphonium bromide 
• 100-07-2 4-methoxy-benzoyl chloride 
• 613-84-3 2-hydroxy-5-methylbenzaldehyde 
• 4383-07-7 2-hydroxymethyl-4-methylphenol 

Downstream Products

• 1260505-22-3 (2-bromo-4,5-difluorophenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 1260505-23-4 (4-hydroxyphenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 1260505-26-7 (4-hydroxy-3-methylphenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 1260505-28-9 (4-hydroxy-3-iodophenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 1260505-21-2 (3,5-dichlorophenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 1313886-74-6 (2-hydroxy-3-methoxyphenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 1260505-24-5 (3-hydroxy-5-methoxyphenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 1260505-15-4 (3,4,5-trimethoxyphenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 1260505-19-8 (4-chlorophenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 1260505-13-2 (4-methoxyphenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 1260505-20-1 (2-bromophenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 1260505-14-3 (3,5-dimethoxyphenyl)(2-(4-methoxy-phenyl)-5-methylbenzofuran-3-yl)methanone 
• 1260505-16-5 (2,3-dimethoxyphenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 

Relevant articles and documents

A new synthesis of 2-aryl/alkylbenzofurans by visible light stimulated intermolecular Sonogashira coupling and cyclization reaction in water

A visible light induced rapid one pot intermolecular Sonogashira coupling and 5-endo-dig cyclization in water of ortho-halophenols and terminal alkynes catalyzed by [Pd] have been developed to furnish 2-aryl/alkyl benzofurans in good yields sans Ru or Ir

Preparation method of multi-substituted benzofuran derivative

The invention provides a preparation method of a multi-substituted benzofuran derivative. The multi-substituted benzofuran derivative is obtained by taking end alkyne and a halogenated phenol derivative as starting raw materials, copper salt as a catalyst and amino acid as an additive and performing coupling reaction in an organic solvent under the condition of adding alkali, wherein the catalystis CuX, X is iodine or bromine, the molar ratio of the catalyst to the halogenated phenol derivative is (0.001-0.5):1, the molar ratio of the amino acid to the catalyst is (0.1-3):1, the molar ratio of the halogenated phenol derivative to the end alkyne is (1-1.5):1, and the reaction temperature is 30 to 150 DEG C. An expensive palladium catalyst liable to cause environmental pollution is not used. The method is simple in process and high in operability, and has a good industrial application prospect.

Fluorination of 2-substituted benzo[b]furans with Selectfluor

An efficient protocol was developed to access 3-fluoro-2-hydroxy-2-substituted benzo[b]furans with Selectfluor as the fluorinating reagent in MeCN and water. By utilizing SOCl2/Py as the dehydrating agent, the compounds above were readily conve