200616-38-2

Basic information

• Product Name: N-Alpha-Fmoc-L-glutamic acid gamma-succinimide ester alpha-tert-butyl ester
• Synonyms: N-Alpha-Fmoc-L-glutamic acid gamma-succinimide ester alpha-tert-butyl ester;Fmoc-L-Glu(OSu)-OtBu;Fmoc-L-glutamic acid γ-N-hydroxysuccinimide ester α-tert-butyl ester≥ 97% (Assay)
• CAS NO: 200616-38-2
• Molecular Formula: C28H30N2O8
• Molecular Weight: 522.5464
• Mol File: 200616-38-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Alpha-Fmoc-L-glutamic acid gamma-succinimide ester alpha-tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Alpha-Fmoc-L-glutamic acid gamma-succinimide ester alpha-tert-butyl ester(200616-38-2)
• EPA Substance Registry System: N-Alpha-Fmoc-L-glutamic acid gamma-succinimide ester alpha-tert-butyl ester(200616-38-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 200616-38-2(Hazardous Substances Data)

Usage

Description

N-Alpha-Fmoc-L-glutamic acid gamma-succinimide ester alpha-tert-butyl ester, commonly referred to as Fmoc-glu(osu)-otbu, is a chemical compound with the appearance of a white to off-white powder. It is a derivative of L-glutamic acid, an essential amino acid, and is characterized by its gamma-succinimide ester and alpha-tert-butyl ester functional groups. N-Alpha-Fmoc-L-glutamic acid gamma-succinimide ester alpha-tert-butyl ester is known for its potential applications in various fields, particularly in the pharmaceutical and chemical industries.

Uses

Used in Pharmaceutical Industry:
Fmoc-glu(osu)-otbu is used as an anti-influenza reagent, playing a crucial role in the development of treatments and preventive measures against influenza infections. Its chemical structure allows it to interact with specific targets in the influenza virus, thereby inhibiting its replication and spread.
Used in Chemical Synthesis:
In the chemical industry, Fmoc-glu(osu)-otbu serves as an important building block for the synthesis of various complex molecules, including peptides, pharmaceuticals, and other bioactive compounds. Its unique functional groups enable it to participate in a range of chemical reactions, making it a versatile component in the synthesis of novel molecules with potential applications in various fields.
Used in Research and Development:
Fmoc-glu(osu)-otbu is also utilized in research and development settings, where it can be employed to study the structure-activity relationships of various biologically active molecules. Its unique properties make it a valuable tool for understanding the mechanisms of action of different compounds and for designing new molecules with improved efficacy and selectivity.

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 84793-07-7 Fmoc-Glu-OtBu 
• 45120-30-7 L-glutamic acid α-tert-butyl ester 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 

Downstream Products

• 1071429-55-4 N2-N,N-dimethylaminomethylene-10-formyl-Pte-Glu(NH(Boc-His(τ-Bu-4-yl)OMe))-OtBu 
• 1046806-32-9 (S)-4-(4-(4-((S)-2-amino-2-carboxyethyl)-1H-imidazol-1-yl)butylcarbonylamino)-2-(4-((2-amino-4-oxo-3,4-dihydropteridin-6-yl)methylamino)benzamido)-4-oxobutanoic acid 

Relevant articles and documents

Metal ion-directed cooperative triple helix formation of glutamic acid-Oligonucleotide conjugate [7]

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