20190-03-8

Basic information

• Product Name: CYCLOHEXYLAMINE CARBONATE
• Synonyms: cyclohexyl-carbamicacicompd.withcyclohexanamine(1:1);CYCLOHEXYLAMINE CARBONATE;CHC ;cyclohexylammonium cyclohexylcarbamate;Carbamic acid, cyclohexyl-, compd. with cyclohexanamine (1:1);Cyclohexylammonium N-cyclohexylcarbamate;Cyclohexylcarbamic acid compd. withcyclohexanamine (1:1);Carbamic acid, N-cyclohexyl-, compd. with cyclohexanamine (1:1)
• CAS NO: 20190-03-8
• Molecular Formula: C₆H₁₃N*C₇H₁₃NO₂
• Molecular Weight: 242.36
• EINECS: 243-571-3
• Mol File: 20190-03-8.mol
• Article Data: 12

Chemical Properties

• Melting Point: 112-113 °C
• Boiling Point: 395°Cat760mmHg
• Flash Point: 192.7°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 2.42E-07mmHg at 25°C
• CAS DataBase Reference: CYCLOHEXYLAMINE CARBONATE(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOHEXYLAMINE CARBONATE(20190-03-8)
• EPA Substance Registry System: CYCLOHEXYLAMINE CARBONATE(20190-03-8)

Safety Data

• Hazardous Substances Data: 20190-03-8(Hazardous Substances Data)

Usage

General Description

Cyclohexylamine carbonate is a chemical compound that is used as a buffering agent, pH adjuster, and corrosion inhibitor in various industrial processes and applications. It is a crystalline solid that is soluble in water and has a strong ammonia-like odor. Cyclohexylamine carbonate is commonly used in the manufacture of pharmaceuticals, dyes, and pigments, as well as in the production of metal cleaning and descaling agents. It is also utilized as an intermediate in the synthesis of organic compounds and in the formulation of specialty chemicals for the agricultural and personal care industries. While it is considered to be a relatively low toxicity compound, proper handling and personal protective equipment are recommended when working with cyclohexylamine carbonate to avoid potential health hazards.

InChI:InChI=1/C7H13NO2.C6H13N/c9-7(10)8-6-4-2-1-3-5-6;7-6-4-2-1-3-5-6/h6,8H,1-5H2,(H,9,10);6H,1-5,7H2

Upstream product

• 124-38-9 carbon dioxide 
• 108-91-8 cyclohexylamine 

Downstream Products

• 124-38-9 carbon dioxide 
• 108-91-8 cyclohexylamine 
• 7107-58-6 benzyl N-cyclohexylcarbamate 
• 3173-53-3 Cyclohexyl isocyanate 
• 55390-61-9 3-cyclohexyl-oxazolidin-2-one 
• 33739-91-2 N-cyclohexyl-4-methoxybenzamide 
• 10264-23-0 N-cyclohexyl-3-phenylpropionamide 
• 5817-68-5 cyclohexyl-carbamic acid methyl ester 
• 100-60-7 N-methylcyclohexylamine 
• 56475-81-1 methyl N-cyclohexyl-N-methylcarbamate 
• 30593-25-0 N-(trimethylsilyl)carbamatocyclohexane 

Relevant articles and documents

Crystal chemistry of 1:1 molecular complexes of carbamate salts formed by slow aerial carbonation of amines

Amines do have rare tendency to undergo aerial carbonation to form carbamic acid. Four different 1:1 molecular complex of carbamate salts reported herein obtained by the aerial carbonation of cyclic amines. X-ray crystal structures show a systematic change in the molecular structure did bring some gradual supramolecular change from one structural motif to another.

Atmospheric Pressure of CO2 as Protecting Reagent and Reactant: Efficient Synthesis of Oxazolidin-2-ones with Carbamate Salts, Aldehydes and Alkynes

Carbon dioxide (CO2) has been wildly employed as an environmentally benign C1 resource for organic synthesis in the recent years. The capture of CO2 with primary amines easily provides the corresponding carbamate salts. We described herein that carbamate salts are a useful reactant for the synthesis of oxazolidin-2-ones via the reaction with aromatic aldehydes and aromatic terminal alkynes. A variety of oxazolidin-2-ones with different functional groups were synthesized in 68-91% yields with only a 5 mol% amount of CuI as catalyst. It was found that the synergetic effect of iodide is important for the transformation. Notable, the captured CO2 serves not only as a protecting reagent for electron-rich primary amine to avoid catalyst poisoning, but also as a reactant for the construction of oxazolidin-2-ones.

Direct NHC-catalysed redox amidation using CO2 for traceless masking of amine nucleophiles

The N-heterocyclic carbene (NHC)-catalysed redox amidation reaction is poorly developed and usually requires catalytic co-additives for electron-rich amine nucleophiles. We report a masking strategy (using CO2) that couples release of the free amine nucleophile to catalytic turnover, and in doing so, enables direct catalytic redox amidation of electron-rich amines.