2050-25-1 Usage
Description
2-[2-(Benzyloxy)ethoxy]ethanol, also known as Benzyl-PEG3-alcohol, is a PEG (polyethylene glycol) linker with an acid-labile benzyl protecting group and a reactive primary alcohol. The primary alcohol allows for further derivatization of the compound, while the hydrophilic PEG linker enhances its water solubility in aqueous media. It is a colorless to light yellow liquid and is commonly used in various applications due to its unique properties.
Uses
Used in Polymer Synthesis:
2-[2-(Benzyloxy)ethoxy]ethanol is used as an initiator in the preparation of linear-PLA (poly(L-lactide)) for enhancing the properties of the resulting polymer.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-[2-(Benzyloxy)ethoxy]ethanol is used as a protecting group for various chemical reactions, particularly in the synthesis of complex molecules. The acid-labile benzyl group can be selectively removed under acidic conditions, allowing for the controlled release of the active compound.
Used in Drug Delivery Systems:
2-[2-(Benzyloxy)ethoxy]ethanol is used as a component in the design of drug delivery systems, where its hydrophilic PEG linker can improve the solubility and bioavailability of drugs in the body. This can lead to enhanced therapeutic outcomes and reduced side effects.
Used in Chemical Synthesis:
In chemical synthesis, 2-[2-(Benzyloxy)ethoxy]ethanol is used as a versatile building block for the creation of various compounds, taking advantage of its reactive primary alcohol and acid-labile benzyl group for further functionalization and protection of sensitive functional groups.
Used in Cosmetics and Personal Care Industry:
In the cosmetics and personal care industry, 2-[2-(Benzyloxy)ethoxy]ethanol is used as an ingredient in formulations due to its ability to improve the solubility of other components, enhance the stability of the final product, and provide a pleasant texture and feel to the consumer.
Check Digit Verification of cas no
The CAS Registry Mumber 2050-25-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,5 and 0 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2050-25:
(6*2)+(5*0)+(4*5)+(3*0)+(2*2)+(1*5)=41
41 % 10 = 1
So 2050-25-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H16O3/c12-6-7-13-8-9-14-10-11-4-2-1-3-5-11/h1-5,12H,6-10H2
2050-25-1Relevant articles and documents
Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses thereof
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Page/Page column 108; 110, (2019/11/11)
Disclosed are an antibody drug conjugate IB, which uses ether linkages for connection, and improves the water solubility, stability and cytotoxicity in vivo and in intro, and an intermediate, a pharmaceutical composition, and uses of the antibody drug conjugate. The antibody drug conjugate has simple synthetic steps and a high yield.
Aryl substituted phosphorothio amine derivatives and their use in medical application
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Paragraph 0149-0153, (2017/09/12)
The invention relates to an aryl-substituted phosphonaminate and an application of the aryl-substituted phosphonaminate in medical science, in particular to an aryl-substituted phosphonaminate showed in a general formula (I), stereoisomer of the aryl-subs
8034
Suthagar, Kajitha,Watson, Andrew J.A.,Wilkinson, Brendan L.,Fairbanks, Antony J.
, p. 153 - 166 (2015/08/24)
Abstract A series of arabinose glycosyl sulfamides with varying alkyl chain types and lengths were synthesised as mimics of decaprenolphosphoarabinose (DPA), and as potential inhibitors of mycobacterial cell wall biosynthesis. Unprecedented conversion of
