20887-06-3

Basic information

• Product Name: N-(2-aminobenzyl)aniline
• Synonyms: N-(2-aminobenzyl)aniline
• CAS NO: 20887-06-3
• Molecular Weight: 198.268
• Mol File: 20887-06-3.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: N-(2-aminobenzyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-aminobenzyl)aniline(20887-06-3)
• EPA Substance Registry System: N-(2-aminobenzyl)aniline(20887-06-3)

Safety Data

• Hazardous Substances Data: 20887-06-3(Hazardous Substances Data)

Usage

General Description

N-(2-aminobenzyl)aniline is a chemical compound with the molecular formula C13H13N. It is an aromatic amine that consists of an aniline moiety with an additional amino group attached to the benzene ring at the 2-position. N-(2-aminobenzyl)aniline is used in the synthesis of dyes, pharmaceuticals, and other organic compounds. It is also used as a building block in organic chemistry and serves as a valuable intermediate in various chemical reactions. N-(2-aminobenzyl)aniline is important in the field of organic synthesis and has applications in the production of a wide range of chemical products.

Upstream product

• 33331-19-0 N-(2-nitrobenzyl)aniline 
• 17064-77-6 N-(2-nitrobenzylidene)aniline 
• 4424-17-3 2-aminobenzanilide 
• 64-17-5 ethanol 
• 141-78-6 ethyl acetate 
• 622-14-0 N,N'-diphenylmethylenediamine 
• 1120-82-7 pyrazole-1-methanol 
• 62-53-3 aniline 
• 552-89-6 2-nitro-benzaldehyde 
• 612-23-7 2-nitrobenzyl chloride 
• 7647-01-0 hydrogenchloride 
• 64-19-7 acetic acid 
• 3682-71-1 2-phenyl-2H-indazole 
• 56222-13-0 N-(2-Phenylaminomethyl-phenyl)-hydroxylamine 

Downstream Products

• 28220-33-9 3-phenyl-3,4-dihydro-1H-quinazoline-2-thione 
• 1280219-73-9 3-phenyl-2-(4-trifluoromethyl-phenyl)-3H-quinazolin-4-one 
• 2385-23-1 2-Methyl-3-phenyl-4(3H)-quinazolinone 
• 5260-41-3 2-ethyl-3-phenyl-3H-quinazolin-4-one 
• 22686-82-4 2,3-diphenyl-3H-quinazolin-4-one 
• 77796-33-9 2-(4-methylphenyl)-3-phenylquinazolin-4(3H)-one 

Relevant articles and documents

Non-catalytic alkylation of phenol and aniline with 1-hydroxymethylpyrazole

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Integration of Bromine and Cyanogen Bromide Generators for the Continuous-Flow Synthesis of Cyclic Guanidines

A continuous-flow process for the in situ on-demand generation of cyanogen bromide (BrCN) from bromine and potassium cyanide that makes use of membrane-separation technology is described. In order to circumvent the handling, storage, and transportation of elemental bromine, a continuous bromine generator using bromate–bromide synproportionation can optionally be attached upstream. Monitoring and quantification of BrCN generation was enabled through the implementation of in-line FTIR technology. With the Br2 and BrCN generators connected in series, 0.2 mmol BrCN per minute was produced, which corresponds to a 0.8 m solution of BrCN in dichloromethane. The modular Br2/BrCN generator was employed for the synthesis of a diverse set of biologically relevant five- and six-membered cyclic amidines and guanidines. The set-up can either be operated in a fully integrated continuous format or, where reactive crystallization is beneficial, in semi-batch mode.

Synthesis of 3h-quinazolin-4-ones and 4h-3,1-benzoxazin-4-ones via benzylic oxidation and oxidative dehydrogenation using potassium iodide-tert-butyl hydroperoxide

A simple and elegant method for benzylic activation was demonstrated employing the potassium iodide/tert-butyl hydrogen peroxide catalytic system. This methodology was further extended for the synthesis of biologically important heterocycles namely, 3H-quinazolin-4-ones and 4H-3,1-benzoxazin-4-ones including mecloqualone and etaqualone which are important quinazolinone-based drugs used for the treatment of insomnia in good yields.