2110-78-3Relevant articles and documents
Palladium(II)-Catalyzed Cyclocarbonylation of Enol Ester of Acetone. A Novel Synthesis of 1,3-Dioxolan-4-one
Kudo, Kiyoshi,Mitsuhashi, Koichi,Mori, Sadayuki,Komatsu, Koichi,Sugita, Nobuyuki
, p. 1615 - 1618 (1993)
The cyclocarbonylation of isopropenyl acetate(1) to produce 2-methoxy-2,5,5-trimethyl-1,3-dioxolan-4-one(2) by use of palladium(II)-phoshine catalyst with methanol in benzene solution was studied at 100 degC under 200 atm of CO.Conversion of 1 up to 98percent and yield to 2 as high as 67percent were attained.
Flow-Assisted Synthesis: A Key Fragment of SR 142948A
Kitching, Matthew O.,Dixon, Olivia E.,Baumann, Marcus,Baxendale, Ian R.
, p. 6540 - 6553 (2017/09/13)
We report a series of multi-step flow operations to deliver an advanced hydrazine intermediate used in the assembly of the neurotensin modulator SR 142948A. Several new reactor configurations have enabled chemical transformations that would be otherwise difficult or dangerous to perform at scale. Overall the flow approach has allowed the preparation of kilogram quantities of the required hydrazine through a short and efficient route.
MONOMER, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS
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, (2014/03/21)
A polymer comprising recurring units derived from a (meth)acrylate monomer of tertiary ester type having branched alkyl on alicycle is used to form a resist composition. When subjected to exposure, PEB and organic solvent development, the resist composition is improved in dissolution contrast.