21762-51-6

Basic information

• Product Name: N-(4-chloro-benzoyl)-2-hydroxy-benzamide
• Synonyms: N-(4-chloro-benzoyl)-2-hydroxy-benzamide
• CAS NO: 21762-51-6
• Molecular Weight: 275.691
• Mol File: 21762-51-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-chloro-benzoyl)-2-hydroxy-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chloro-benzoyl)-2-hydroxy-benzamide(21762-51-6)
• EPA Substance Registry System: N-(4-chloro-benzoyl)-2-hydroxy-benzamide(21762-51-6)

Safety Data

• Hazardous Substances Data: 21762-51-6(Hazardous Substances Data)

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 65-45-2 salicylamide 

Downstream Products

• 120029-44-9 2-[5-(4-Chloro-phenyl)-2-phenyl-2H-[1,2,4]triazol-3-yl]-phenol 
• 79349-26-1 3-(4-chlorophenyl)-5-(2-hydroxyphenyl)-1,2,4-oxadiazole 
• 21762-48-1 2-(4-chlorophenyl)-4H-benzo[e][1,3]oxazin-4-one 

Relevant articles and documents

Synthesis of Some 2-Aryl-1,2,4-triazolobenzoxazin-5-ones as Tools To Define the Essential Pharmacophoric Descriptors of a Benzodiazepine Receptor Ligand

The synthesis and benzodiazepine receptor (BZR) affinity of some 1,2,4-triazolo-benzoxazin-5-ones, 2-22, are reported.Compounds 2-22 are devoid of the proton donor group, which according to a BZR schematic model was one of the pharmacophoric descriptors for receptor-ligand interaction.The binding data show that 2-(2-fluorophenyl)-9-chloro-1,2,4-triazolobenzoxazin-5-one (12) and some other compounds display nanomolar BZR affinity, indicating that the hydrogen donor group is not essential for the anchoring of 6,6,5-tricyclic systems to the BZR but only affects the potency of a ligand.