21769-81-3

Basic information

• Product Name: 1H-Pyrazolo[1,2-b]phthalazine-5,10-dione, 2,3-dihydro-
• CAS NO: 21769-81-3
• Molecular Formula: C11H10N2O2
• Molecular Weight: 202.213
• Mol File: 21769-81-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazolo[1,2-b]phthalazine-5,10-dione, 2,3-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazolo[1,2-b]phthalazine-5,10-dione, 2,3-dihydro-(21769-81-3)
• EPA Substance Registry System: 1H-Pyrazolo[1,2-b]phthalazine-5,10-dione, 2,3-dihydro-(21769-81-3)

Safety Data

• Hazardous Substances Data: 21769-81-3(Hazardous Substances Data)

Upstream product

• 133056-80-1 2-(3-Hydroxypropyl)-4-(2'-hydroxyethylamino)phthalazin-1(2H)-one 
• 98-88-4 benzoyl chloride 

Relevant articles and documents

Chain length dependent reactivity of 2-(ω-hydroxyalkyl)-4-(ω'-hydroxyalkylamino)phthalazin-1(2H)-ones in azeotropic hydrobromic acid

In boiling 48% HBr conversions of title compounds (5a-f) resulted in 2-(ω-bromoalkyl)-4-(2-hydroxyethylamino)-phthalazinones 8a,c, angular tricycles 7a,c-f and the 14a tricyclic dione, respectively, depending on the lengths of the side chains and the reaction time applied. The large difference between the reactivities of 4-(2-hydroxyethylamino)- and 4-(3-hydroxypropylamino) homologues in the exchange OH → Br was interpreted on the basis of the relative OH-basicities in the N3-protonated molecules. The proposed mechanism for the conversion to 14a involving a Smiles-type rearrangement was supported by additional experiments with 4-amino-2-(ω-hydroxyalkyl)-phthalazinones 15a,b.