21905-73-7

Basic information

• Product Name: 2-(2-METHOXYPHENOXY)BENZOIC ACID
• Synonyms: 2-(2-METHOXYPHENOXY)BENZOIC ACID;AKOS BBS-00001148;Benzoic acid, 2-(2-methoxyphenoxy)-;Benzoic acid, o-(o-methoxyphenoxy)-
• CAS NO: 21905-73-7
• Molecular Formula: C₁₄H₁₂O₄
• Molecular Weight: 244.24
• Mol File: 21905-73-7.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-(2-METHOXYPHENOXY)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-METHOXYPHENOXY)BENZOIC ACID(21905-73-7)
• EPA Substance Registry System: 2-(2-METHOXYPHENOXY)BENZOIC ACID(21905-73-7)

Safety Data

• Hazardous Substances Data: 21905-73-7(Hazardous Substances Data)

Usage

Chemical Class

Non-steroidal anti-inflammatory drugs (NSAIDs)
This compound belongs to a class of drugs that are known for their anti-inflammatory and pain-relieving properties.

Common Uses

Medication for reducing pain, inflammation, and fever
Meclofenamic acid is primarily used to alleviate these symptoms in various conditions.

Effectiveness in Conditions

Menstrual pain, rheumatoid arthritis, and osteoarthritis
The compound has been found to be effective in treating these specific conditions.

Mechanism of Action

Inhibition of prostaglandin production
Meclofenamic acid works by inhibiting the production of prostaglandins, which are responsible for causing pain and inflammation in the body.

Importance in Pharmaceutical Industry

Development of anti-inflammatory and analgesic medications
Due to its mechanism of action and therapeutic effects, Meclofenamic acid is a valuable chemical in the creation of new medications for inflammation and pain relief.

Upstream product

• 610-96-8 methyl chlorobenzoate 
• 394-47-8 2-fluorobenzonitrile 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 79365-16-5 2-(2'-methoxyphenoxy)benzonitrile 
• 90-05-1 2-methoxy-phenol 
• 88-67-5 2-Iodobenzoic acid 
• 88-65-3 2-bromobenzoic-acid 
• 13052-77-2 sodium 2-methoxyphenolate 
• 578-57-4 2-bromoanisole 
• 17264-74-3 sodium 2-chlorobenzoate 
• 118-91-2 ortho-chlorobenzoic acid 
• 62256-40-0 2-(2-methoxyphenoxy)benzaldehyde 
• 26321-29-9 2-methoxy-2'-methyldiphenyl ether 

Downstream Products

• 55482-89-8 Guaiaspir 
• 87-16-1 2-methoxyphenyl 2-hydroxybenzoate 
• 1417408-73-1 C₂₇H₂₈N₂O₄*ClH 
• 1417408-72-0 4-(3-(4-(2-methoxyphenyl)piperazine-1-yl)propoxy)-9H-xanthen-9-one hydrochloride 
• 1417408-70-8 (R,S)-4-(2-acetoxy-3-(4-(2-methoxyphenyl)piperazine-1-yl)propoxy)-9H-xanthen-9-one hydrochloride 
• 1417408-67-3 (R,S)-4-(2-hydroxy-3-(4-(2-methoxyphenyl)piperazine-1-yl)propoxy)-9H-xanthen-9-one hydrochloride 
• 118793-87-6 4-(4-methylaminobutoxy)xanthone 
• 6702-58-5 4-methoxy-9H-xanthen-9-one 
• 14686-63-6 4-hydroxy-9H-xanthen-9-one 

Relevant articles and documents

Hydrophobicity constants for several xanthones and flavones

The octanol-water distribution of several xanthones and flavones was studied. Their hydrophobicity constants (log P) were determined. The lipophilicity constants (π) of the substituents were calculated. The relationship between the structure and hydrophobicity constants of the gamma-pyrone derivatives was found.

Electrochemical Reductive Smiles Rearrangement for C-N Bond Formation

A conceptually new and synthetically valuable radical Smiles rearrangement reaction is reported under undivided electrolytic conditions. This protocol employs an entirely new strategy for the electrochemical radical Smiles rearrangement. Remarkably, an amidyl radical generated from the cleavage of the N-O bond under reductive electrolytic conditions plays a crucial role in this transformation. Various hydroxylamine derivatives bearing different substituents are suitable in this electrochemical transformation, furnishing the corresponding amides in up to 86% yield.

A photoredox-neutral Smiles rearrangement of 2-aryloxybenzoic acids

We report on the use of visible light photoredox catalysis for the radical Smiles rearrangement of 2-aryloxybenzoic acids to obtain aryl salicylates. The method is free of noble metals and operationally simple and the reaction can be run under mild batch or flow conditions. Being a redox neutral process, no stoichiometric oxidants or reductants are needed.