220957-78-8

Basic information

• Product Name: 2,5-Pyrrolidinedione, 1-[[(2E)-3-[3,4-bis(acetyloxy)phenyl]-1-oxo-2-propenyl]oxy]-
• CAS NO: 220957-78-8
• Molecular Formula: C17H15NO8
• Molecular Weight: 361.308
• Mol File: 220957-78-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,5-Pyrrolidinedione, 1-[[(2E)-3-[3,4-bis(acetyloxy)phenyl]-1-oxo-2-propenyl]oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Pyrrolidinedione, 1-[[(2E)-3-[3,4-bis(acetyloxy)phenyl]-1-oxo-2-propenyl]oxy]-(220957-78-8)
• EPA Substance Registry System: 2,5-Pyrrolidinedione, 1-[[(2E)-3-[3,4-bis(acetyloxy)phenyl]-1-oxo-2-propenyl]oxy]-(220957-78-8)

Safety Data

• Hazardous Substances Data: 220957-78-8(Hazardous Substances Data)

Upstream product

• 74124-79-1 di(succinimido) carbonate 
• 88623-81-8 3,4-diacetoxycinnamic acid 
• 331-39-5 caffeic acid 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 

Downstream Products

• 1254929-50-4 (E)-2-(2-(3-(3,4-dihydroxyphenyl)acrylamido)ethoxy)ethyl 4-hydroxy-3,5-dimethoxybenzoate 
• 1254929-49-1 (E)-4-(3-(2-(2-(4-acetoxy-3,5-dimethoxybenzoyloxy)ethoxy)ethylamino)-3-oxoprop-1-enyl)-1,2-phenylene diacetate 
• 1254929-48-0 (E)-2-(2-((E)-3-(3,4-dihydroxyphenyl)acrylamido)ethoxy)ethyl 3-(4-hydroxy-3-methoxyphenyl) acrylate 
• 1254929-47-9 4-((E)-3-(2-(2-((E)-3-(4-acetoxy-3-methoxyphenyl)acryloyloxy)ethoxy)ethylamino)-3-oxoprop-1-enyl)-1,2-phenylene diacetate 
• 1254929-61-7 C₁₇H₂₁NO₇ 
• 582311-48-6 2-[3-(3,4-dihydroxy-phenyl)-acryloylamino]-3-(4-hydroxy-phenyl)propionic acid methyl ester 

Relevant articles and documents

A NOVEL NEUROPROTECTIVE AND NEURORESTORATIVE N-PROPARGYL CAFFEAMIDE (PACA) AND USE AS A TREATMENT FOR NEURODEGENERATIVE DISEASES

The present invention is directed to compounds, pharmaceutical compositions, and related methods of treatment and/or prevention for neurodegenerative diseases, such as Parkinson's disease.

Very short and efficient syntheses of the spermine alkaloid kukoamine A and analogs using isolable succinimidyl cinnamates

Direct selective acylation of the primary amino functions of spermine and spermidine with a variety of isolable succinimidyl cinnamates, followed by catalytic hydrogenation, gave high yields of the spermine alkaloid kukoamine A and analogs suitable for structure-activity relationship studies. Suitable succinimidyl cinnamates were readily obtained through Wittig reaction of aromatic aldehydes with the ylides Ph3P=CRCO2Me, followed by saponification and activation with N-hydroxysuccinimide in the presence of N,N'-dicyclohexylcarbodiimide. Copyright