2215-33-0

Basic information

• Product Name: pyridine-2-carbaldehyde-2-pyridylhydrazone
• Synonyms: pyridine-2-carbaldehyde-2-pyridylhydrazone;1-(2-Pyridyl)-2-[(2-pyridyl)methylene]hydrazine;2-[(2-Pyridylhydrazono)methyl]pyridine;2-Pyridinecarbaldehyde 2-pyridinylhydrazone;2-Pyridinecarbaldehyde 2-pyridyl hydrazone;2-Pyridinecarbaldehyde 2-pyridylhydrazone;Picolinaldehyde 2-pyridylhydrazone
• CAS NO: 2215-33-0
• Molecular Formula: C11H10N4
• Molecular Weight: 198.2239
• EINECS: 218-678-3
• Mol File: 2215-33-0.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 378°Cat760mmHg
• Flash Point: 182.4°C
• Appearance: /
• Density: 1.15g/cm³
• Vapor Pressure: 6.48E-06mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: pyridine-2-carbaldehyde-2-pyridylhydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: pyridine-2-carbaldehyde-2-pyridylhydrazone(2215-33-0)
• EPA Substance Registry System: pyridine-2-carbaldehyde-2-pyridylhydrazone(2215-33-0)

Safety Data

• Hazardous Substances Data: 2215-33-0(Hazardous Substances Data)

Usage

Description

Pyridine-2-carbaldehyde-2-pyridylhydrazone is a chemical compound that is commonly used as a chelating agent in various chemical reactions and industrial processes. It is a derivative of pyridine and is characterized by its ability to form stable complexes with metal ions, making it useful in analytical chemistry, especially for the determination and extraction of metal ions in solution. It is also used as a reagent in organic synthesis, particularly in the preparation of heterocyclic compounds, and as an intermediate in the production of pharmaceuticals and agrochemicals. Additionally, pyridine-2-carbaldehyde-2-pyridylhydrazone has been studied for its potential applications in corrosion inhibition and as a fluorescent probe in biological imaging.

Uses

Used in Analytical Chemistry:
Pyridine-2-carbaldehyde-2-pyridylhydrazone is used as a chelating agent for the determination and extraction of metal ions in solution, due to its ability to form stable complexes with metal ions.
Used in Organic Synthesis:
Pyridine-2-carbaldehyde-2-pyridylhydrazone is used as a reagent in the preparation of heterocyclic compounds, contributing to the synthesis of various organic compounds.
Used in Pharmaceutical and Agrochemical Production:
Pyridine-2-carbaldehyde-2-pyridylhydrazone is used as an intermediate in the production of pharmaceuticals and agrochemicals, playing a crucial role in the synthesis of these compounds.
Used in Corrosion Inhibition:
Pyridine-2-carbaldehyde-2-pyridylhydrazone has been studied for its potential applications in corrosion inhibition, offering a possible solution for protecting materials from corrosion.
Used in Biological Imaging:
Pyridine-2-carbaldehyde-2-pyridylhydrazone has been studied as a fluorescent probe in biological imaging, which could be utilized for visualizing and tracking specific biological processes or structures.

InChI:InChI=1/C11H10N4/c1-3-7-12-10(5-1)9-14-15-11-6-2-4-8-13-11/h1-9H,(H,13,15)/b14-9-

Upstream product

• 1121-60-4 pyridine-2-carbaldehyde 
• 4930-98-7 pyrid-2-ylhydrazine 
• 62437-99-4 2-hydrazinylpyridine dihydrochloride 
• 21945-37-9 E-pyridine-2-carbaldehyde 2-pyridylhydrazone 
• 14336-71-1 calcium chloride 
• 30915-38-9 (E)-1-(2-pyridinyl)methylene-2-phenylhydrazine 
• 30915-37-8 (Z)-2-pyridine-carbaldehyde phenylhydrazone 
• 109-04-6 2-bromo-pyridine 
• 504-29-0 2-aminopyridine 
• 372-48-5 2-fluoropyridine 
• 21945-38-0 Z-pyridine-2-carbaldehyde 2'-pyridylhydrazone 

Downstream Products

• 21945-37-9 E-pyridine-2-carbaldehyde 2-pyridylhydrazone 
• 5006-54-2 5-(2'-pyridyl)-s-triazolo<4,3-a>pyridine 
• 95526-16-2 N'-acetyl-N'-(4-nitrophenyl)pyridine-2-carbohydrazide 
• 21945-38-0 Z-pyridine-2-carbaldehyde 2'-pyridylhydrazone 

Relevant articles and documents

New copper(II) complexes of pyridine-2-carboxaldehyde-N-(2-pyridyl)hydrazone and 2-hydroxy-1-naphthaldehyde-semicarbazone: Synthesis, characterization, DNA binding and antimicrobial activity studies

Two new copper(II) complexes of pyridine-2-carboxaldehyde-N-(2-pyridyl)hydrazone [Cu(PCPH)(H2O)2](NO3)(H2O)2 (1) and 2-hydroxy-1-naphthaldehyde-semicarbazone [Cu(II)(HNSC)H2O]·NO3·H2O (2) have been synthesized and characterized by spectroscopic techniques and single crystal X-ray diffraction study. Complex 1 crystallized as square pyramidal coordination complex in triclinic crystal system while complex 2 crystallized as square planar complex in monoclinic crystal system. EPR spectral patterns are of normal order of energy levels, i.e. x2-y2 >> z2 > xy > xz, yz, with partial covalent character. Both copper(II) complexes were found to be groove binding to calf-thymus DNA and showed activity against E. coli, S. aureus, B. cereus and E. faccium.

Determination of the binding constants of propeller-like metal complexes of picolinaldehyde-2-pyridylhydrazone

Herein, we determined the binding constants for transition metal complexes of Cu2+, Co2+, Fe2+, Ni2+, and Zn2+ ions formed with the ligand picolinaldehyde-2-pyridylhydrazone (PapyH) using the Benesi-Hildebrand method. Stoichiometry 2:1 (ligand: metal) was previously determined by the Job's method and confirmed by single-crystal X-ray diffraction finding a propeller-like structure of the [Fe(Papy)2] compound. PapyH and the metal complexes were characterized by 1H NMR and UV-Vis spectroscopy, respectively. The Cu2+ complex exhibited the highest stability constant, which was confirmed by competitive reaction of different metal ions with the ligand PapyH.

Synthesis and antimycobacterial evaluation of pyridinyl- and pyrazinylhydrazone derivatives

Bioisosteric replacements are often tried goaling to affect the lipophilicity, polarity, and aqueous solubility of the substances, as a way to obtain therapeutically improved medicines. Also, hydrazonyl compounds are described with a wide range of pharmac