22530-83-2

Basic information

• Product Name: Cyclohexane, 1-azido-1-methyl-
• CAS NO: 22530-83-2
• Molecular Formula: C7H13N3
• Molecular Weight: 139.2
• Mol File: 22530-83-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Cyclohexane, 1-azido-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexane, 1-azido-1-methyl-(22530-83-2)
• EPA Substance Registry System: Cyclohexane, 1-azido-1-methyl-(22530-83-2)

Safety Data

• Hazardous Substances Data: 22530-83-2(Hazardous Substances Data)

Upstream product

• 1192-37-6 methylenecyclohexane 
• 591-49-1 1-methylcyclohex-1-ene 
• 590-67-0 1-Methylcyclohexanol 
• 4648-54-8 trimethylsilylazide 
• 931-78-2 1-chloro-1-methylcyclohexane 

Downstream Products

• 89854-70-6 1-methylcyclohexanamine hydrochloride 
• 118132-86-8 1-Methyl-cyclohexyl-phosphorimidic acid triethyl ester 
• 6526-78-9 1-methyl-1-cyclohexylamine 
• 118132-92-6 (1-Methyl-cyclohexyl)-phosphoramidic acid diethyl ester 
• 118132-96-0 Toluene-4-sulfonic acid; compound with 1,1-dimethyl-2-phenyl-ethylamine 

Relevant articles and documents

Synthesis and structure-affinity relationships of 1,3,5-alkylsubstituted cyclohexylamines binding at NMDA receptor PCP site

A series of 1,3,5-alkylsubstituted cyclohexylamines 2 were synthesized as ligands for the N-methyl-D-aspartate (NMDA) receptor phencyclidine (PCP) binding site. Pure diastereomers with defined configuration of amino group 2- ax and 2-eq were obtained. The optimal size of 1,3,5-substituents was determined for cyclohexylamines 2 with an equatorial amino group in the lowest energy conformation using Hansch analysis. According to the data, the lipophilic part of cyclohexylamines 2 does not discriminate between hydrophobic regions of the PCP binding site but rather recognizes this site as a whole lipophilic pocket. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

Conversion of alkenes and alcohols to azides over zeolite-supported sodium azide

Zeolite-supported sodium azide reagents are versatile catalysts for the conversion of various alkenes and alcohols to the corresponding azides in good yield under mild conditions.

IMINOPHOSPHORANE-MEDIATED TRANSFORMATION OF TERTIARY ALCOHOLS INTO t-ALKYLAMINES AND THEIR N-PHOSPHORYLATED DERIVATIVES

Novel azidation of tertiary alcohols by means of trimetylsilyl azide in the presence of boron trifluoride etherate has been worked out.The Staudinger reaction of crude azides with triethyl phosphite affords the corresponding iminophosphoranes which can be directly transformed into diethyl N-(t-alkyl)phosphoroamidates or t-alkylamine tosylates.