225650-39-5Relevant articles and documents
Synergistic Catalysis: Metal/Proton-Catalyzed Cyclization of Alkynones Toward Bicyclo[3.n.1]alkanones
Zhu, Shifa,Zhang, Qiaohui,Chen, Kai,Jiang, Huanfeng
, p. 9414 - 9418 (2015/08/06)
A highly efficient and practical synergistically metal/proton-catalyzed Conia-ene reaction for the synthesis of bicyclo[3.n.1]alkanones has been developed. This synergistic catalysis was successfully utilized in modifying natural compounds such as methyl dihydrojasmonate, α,β-thujone, and 5α-cholestan-3-one. Furthermore, the bridged carbonyl group of bicyclo[3.2.1]alkanones could be easily attacked by nucleophiles to give the ring-opened cycloheptenone products or bicyclo[4.2.1]amide in excellent yields. These reactions provide rapid access to a diverse range of cyclic structures from simple starting materials or naturally occurring compounds. A highly efficient and practical synergistically metal/proton-catalyzed Conia-ene reaction for the synthesis of bicyclo[3.n.1]alkanones has been developed. The reaction was successfully utilized in modifying natural compounds such as methyl dihydrojasmonate, α,β-thujone, and 5α-cholestan-3-one. Furthermore, the bicyclo[3.2.1]alkanones can be ring-opened by nucleophiles to give the corresponding products in excellent yields.
Synthesis of ring-substituted bis-η5-cyclopentadienyl derivatives of the Group IV elements containing the bicyclic ligands η5-C5H3(1,2-CH2-)n, n=4, 5, or 6
Polo, Eleonora,Bellabarba, Ronan M.,Prini, Giansiro,Traverso, Orazio,Green, Malcolm L.H.
, p. 211 - 218 (2007/10/03)
The synthesis of unsubstituted and substituted bicyclic η5-cyclopentadienyl ligands and their Group IV metal complexes [M{η5-C5H3(1,2-CH2-) n}2Cl2], where n=4, 5, 6 and M=Ti, Zr, Hf, is reported. An example of an ansa-bridged zirconium analogue is also described.
