22581-72-2 Usage
Description
Pyridine, 4-(methylthio)(6CI,8CI,9CI), also known as 4-(methylthio)pyridine, is a chemical compound belonging to the pyridine family, characterized by a six-membered ring with five carbon atoms and one nitrogen atom. The unique addition of a methylthio group at the fourth position of the pyridine ring endows this compound with distinct chemical and physical properties, making it a versatile building block in various industries.
Uses
Used in Pharmaceutical Industry:
Pyridine, 4-(methylthio)(6CI,8CI,9CI) serves as a crucial building block in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications, contributing to the advancement of medicinal chemistry.
Used in Pesticide Industry:
In the agricultural sector, this compound acts as a key component in the production of certain pesticides. Its incorporation into these products can enhance their effectiveness in controlling pests and protecting crops, thereby supporting sustainable agriculture.
Used in Organic Chemistry:
Pyridine, 4-(methylthio)(6CI,8CI,9CI) also functions as a valuable reagent in organic chemistry reactions. Its distinctive properties facilitate specific chemical transformations, making it an essential tool for researchers and chemists in the field.
Used in Food and Beverage Industry:
Leveraging its odor and volatile nature, Pyridine, 4-(methylthio)(6CI,8CI,9CI) finds application as a flavoring agent in the food and beverage industry. It can be used to impart unique flavors and aromas to various products, enhancing consumer appeal.
However, it is imperative to handle and store 4-(methylthio)pyridine with care due to its potential harmful effects if ingested, inhaled, or comes into contact with skin, ensuring safety in all its applications.
Check Digit Verification of cas no
The CAS Registry Mumber 22581-72-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,5,8 and 1 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 22581-72:
(7*2)+(6*2)+(5*5)+(4*8)+(3*1)+(2*7)+(1*2)=102
102 % 10 = 2
So 22581-72-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H7NS/c1-8-6-2-4-7-5-3-6/h2-5H,1H3
22581-72-2Relevant articles and documents
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Thiessen et al.
, p. 153,154,157 (1974)
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Design, synthesis and structure-activity relationship study of novel naphthoindolizine and indolizinoquinoline-5,12-dione derivatives as IDO1 inhibitors
Yang, Rui,Chen, Yu,Pan, Liangkun,Yang, Yanyan,Zheng, Qiang,Hu, Yue,Wang, Yuxi,Zhang, Liangren,Sun, Yang,Li, Zhongjun,Meng, Xiangbao
, p. 4886 - 4897 (2018/09/11)
Indoleamine 2,3-dioxygenase 1 (IDO1) is regarded as a promising target for cancer immunotherapy. Many naphthoquinone derivatives have been reported as IDO1 inhibitors so far. Herein, two series of naphthoquinone derivatives, naphthoindolizine and indolizinoquinoline-5,12-dione derivatives, were synthesized and evaluated for their IDO1 inhibitory activity. Most of the target compounds showed significant inhibition potency and high selectivity for IDO1 over tryptophan 2,3-dioxygenase (TDO). The structure-activity relationship was also summarized. The most potent compounds 5c (IC50 23 nM, IDO1 enzyme), and 5b′ (IC50 372 nM, HeLa cell) were identified as promising lead compounds.
Enzymatic synthesis of novel chiral sulfoxides employing Baeyer-villiger monooxygenases
Rioz-Martinez, Ana,De Gonzalo, Gonzalo,Pazmino, Daniel E. Torres,Fraaije, Marco W.,Gotor, Vicente
experimental part, p. 6409 - 6416 (2011/02/24)
Optically active sulfoxides are compounds of high interest in organic chemistry. Herein, we report the preparation of a set of chiral heteroaryl alkyl, cyclohexyl alkyl, and alkyl alkyl sulfoxides by using enantioselective sulfoxidation reactions employing three Baeyer-Villiger monooxygenases (BVMOs). Careful selection of the reaction conditions, starting sulfide, and biocatalyst can be used to achieve good to excellent enantiomeric excess values. Thus, valuable chiral synthons can be obtained by performing the reactions under mild and environmentally friendly conditions. The most promising biotransformations that employ a BVMO cell-free extract preparation have been developed on a 250-mg scale to give the chiral sulfoxides in high yields in most of the reactions. Copyright
