23661-37-2

Basic information

• Product Name: .alpha.-Cyclodextrin, octadecaacetate
• Synonyms: .alpha.-Cyclodextrin, octadecaacetate;a-Cyclodextrin octadecaacetate
• CAS NO: 23661-37-2
• Molecular Formula: C72H96 O48
• Molecular Weight: 1729.5
• Mol File: 23661-37-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: .alpha.-Cyclodextrin, octadecaacetate(CAS DataBase Reference)
• NIST Chemistry Reference: .alpha.-Cyclodextrin, octadecaacetate(23661-37-2)
• EPA Substance Registry System: .alpha.-Cyclodextrin, octadecaacetate(23661-37-2)

Safety Data

• Hazardous Substances Data: 23661-37-2(Hazardous Substances Data)

Upstream product

• 75-36-5 acetyl chloride 
• 10016-20-3 alpha cyclodextrin 
• 108-24-7 acetic anhydride 

Downstream Products

• 355012-91-8 1^I,2^I-VI,3^I-VI,4^VI,6^I-VI-eicosa-O-acetyl-α-maltohexaose 
• 355012-91-8 icosa-O-acetylmaltohexaose 
• 355012-91-8 peracetylated maltohexaose β-anomer 
• 355012-91-8 peracetylated maltohexaose α-anomer 
• 102671-24-9 icosa-O-acetyl maltohexaose 

Relevant articles and documents

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Complexes of peracetylated cyclodextrin in a non-aqueous aprotic medium: the role of residual water

This paper describes the interaction between aromatic esters and peracetylated cyclodextrins (CDs) studied by NMR spectroscopy in deuterochloroform (CDCl3). The observed chemical shift changes highlight the existence of interactions between an aromatic alkyl ester, water and peracetylated CDs. In some cases, substituent chemical shift determination was influenced by the low water content of CDCl3 and/or the host molecule. Higher CD concentrations resulted in water signal drifts in all studied cases. It was not possible to obtain a completely dry sample of peracetyl γCD: ～1 mol of water remained and the water signal showed reversed movement, with respect to the other two CD analogues, upon increasing host concentration. The estimated 1 : 1 stability constants for the water : peracetyl CD complexes are in the 50-150 M-1 range in CDCl3, but show a relatively large calculation error. The calculated 1 : 1 stability constants for the peracetyl CD : ester complexes are also in this range, but 1 : 2 and 2 : 1 complex compositions are also possible. Overall, our results highlight dynamic aspects of water nanoconfined in a highly hydrophobic environment, thus mimicking biological recognition where a few water molecules often play a pivotal role.

Effective Synthesis and Modification of α-Cyclodextrin-Based [3]Rotaxanes Enabling Versatile Molecular Design

One-pot synthesis of various α-cyclodextrin-(α-CD-) based [3]rotaxanes in water and their structural modifications are discussed in detail. Pseudo[3]rotaxane was prepared from α-CD and α,ω-diaminododecane in water (above 100 g, quantitative yield in a 1 L