23768-17-4

Basic information

• Product Name: N-methyl-2-(pyridin-3-yl)indole
• Synonyms: N-methyl-2-(pyridin-3-yl)indole;1-Methyl-2-pyridin-3-yl-1H-indole
• CAS NO: 23768-17-4
• Molecular Formula: C14H12N2
• Molecular Weight: 208
• Mol File: 23768-17-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-methyl-2-(pyridin-3-yl)indole(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-2-(pyridin-3-yl)indole(23768-17-4)
• EPA Substance Registry System: N-methyl-2-(pyridin-3-yl)indole(23768-17-4)

Safety Data

• Hazardous Substances Data: 23768-17-4(Hazardous Substances Data)

Upstream product

• 626-55-1 3-Bromopyridine 
• 603-76-9 1-methylindole 
• 97-94-9 triethyl borane 
• 157427-46-8 1-methyl-2-(tri-n-butylstannyl)-1H-indole 
• 1120-90-7 3-iodopyridine 
• 75833-63-5 2-iodo-1-methyl-1H-indole 
• 1170697-28-5 nicotinic acid N,N'-dimethyl-N'-phenylhydrazide 
• 19493-09-5 Methylenetriphenylphosphorane 
• 15432-24-3 2-(pyridin-3-yl)-indole 
• 144-55-8 sodium hydrogencarbonate 
• 74-88-4 methyl iodide 

Relevant articles and documents

Novel Aspects on the Reaction of Trialkyl-(1-methylindol-2-yl)borates

A new use of trialkyl-(1-methylindol-2-yl)borates for the synthesis of 2-substituted indoles involving the palladium catalysed cross-coupling with vinylic and aromatic halides, or a facile alkyl migration from boron to carbon without an additional electrophile is described.

Synthesis of indoles via alkylidenation of acyl hydrazides

Indoles have been synthesised via alkylidenation of acyl phenylhydrazides using phosphoranes and the Petasis reagent, followed by in situ thermal rearrangement of the product enehydrazines. The Petasis reagent provides an essentially neutral equivalent of the [acid-catalysed] Fischer indole synthesis, but with acyl phenylhydrazides as starting substrates. Alkylidene triphenylphosphoranes convert aroyl phenylhydrazides to indoles, but acyl phenylhydrazides derived from aliphatic carboxylic acids undergo a Brunner reaction to form indolin-2-ones.

N-hydroxyurea derivative and pharmaceutical composition containing the same

An N-hydroxyurea derivative having an antiallergic action or anti-inflammatory action having the formula wherein, either one of R1, R3, and R4 represents A, either one of the other groups of R1, R3, and R4 and R2 represents a 3-pyridyl group or 3-pyridylalkyl group, the remaining groups of R1, R2, R3, and R4 independently represent a hydrogen atom, halogen atom, or a substituted or unsubstituted C1 to C8 alkyl group, R5 represents a hydrogen atom or lower alkyl group, R6 represents a hydrogen atom, lower alkyl group, C3 to C7 cycloalkyl group, or a substituted or unsubstituted phenyl group, where the substituent represents a halogen atom, lower alkyl group, or lower alkoxy group, B represents a bond, C1 to C20 alkylene group, C2 to C8 alkenylene group, or C2 to C8 alkynylene group or B—C(R5) represents a C2 to C6 alkylene group having a benzene ring in the middle thereof or its pharmacologically acceptable salt or the hydrate or solvate thereof.