2403-27-2

Basic information

• Product Name: (2E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one
• Synonyms: (2E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one;1-(4-Bromophenyl)-3-phenyl-2-propen-1-one;4-Bromophenylstyryl ketone;Styryl(4-bromophenyl) ketone;β-Phenyl-4'-bromoacrylophenone;2-Propen-1-one, 1-(4-bromophenyl)-3-phenyl-;Ai3-16122;Ccris 2220
• CAS NO: 2403-27-2
• Molecular Formula: C₁₅H₁₁BrO
• Molecular Weight: 287.16
• Product Categories: Halides;Phenyls & Phenyl-Het
• Mol File: 2403-27-2.mol
• Article Data: 169

Chemical Properties

• Boiling Point: 402.2°Cat760mmHg
• Flash Point: 82.4°C
• Appearance: /
• Density: 1.393g/cm³
• Vapor Pressure: 1.12E-06mmHg at 25°C
• Refractive Index: 1.646
• CAS DataBase Reference: (2E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one(2403-27-2)
• EPA Substance Registry System: (2E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one(2403-27-2)

Safety Data

• Hazardous Substances Data: 2403-27-2(Hazardous Substances Data)

Usage

Description

(2E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one, also known as 4'-bromoacetophenone, is an organic compound with a molecular formula of C15H11BrO. It is categorized as a ketone and contains a benzene ring with a bromine atom and a phenyl group attached to a carbon-carbon double bond. (2E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one is significant in the field of organic chemistry and drug development.

Uses

Used in Pharmaceutical Industry:
(2E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one is used as a precursor in the synthesis of various pharmaceuticals for its ability to be a building block in creating complex molecules.
Used in Agrochemical Industry:
(2E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one is used as a precursor in the synthesis of various agrochemicals, contributing to the development of new compounds for agricultural applications.
Used in Organic Synthesis:
(2E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one is used as a building block in organic synthesis for creating complex molecules, showcasing its versatility in chemical reactions.
Used in Biological and Pharmacological Research:
(2E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one is utilized in research for its potential biological and pharmacological activities, indicating its importance in scientific studies and drug discovery.

InChI:InChI=1/C15H11BrO/c16-14-9-7-13(8-10-14)15(17)11-6-12-4-2-1-3-5-12/h1-11H/b11-6+

Upstream product

• 99-90-1 para-bromoacetophenone 
• 100-52-7 benzaldehyde 
• 108-86-1 bromobenzene 
• 102-92-1 cinnamoyl chloride 
• 1122-91-4 4-bromo-benzaldehyde 
• 98-86-2 acetophenone 
• 135885-92-6 3-(4-Bromo-benzoyl)-4-(4-bromo-phenyl)-1-cyano-4-hydroxy-2,6-diphenyl-cyclohexanecarboxylic acid ethyl ester 
• 3939-41-1 N-(4-carboxyphenyl)benzylideneimine 
• 66107-30-0 4-bromophenyl trifluoromethanesulfonate 
• 66680-87-3 (E)-1-phenyl-(2-tributylstannyl)ethene 
• 58824-56-9 1-(p-bromophenyl)prop-2-en-1-ol 
• 98-80-6 phenylboronic acid 
• 100-42-5 styrene 
• 19710-56-6 hydroxycarbene 

Downstream Products

• 909081-00-1 [3-(4-bromo-phenyl)-3-oxo-1-phenyl-propyl]-malonic acid dimethyl ester 
• 86516-92-9 6-(4-Bromo-phenyl)-1,3-dimethyl-8-phenyl-7,8-dihydro-1H-pyrimido[4,5-b][1,4]oxazepine-2,4-dione 
• 97691-59-3 6-(4-Bromo-phenyl)-4-phenyl-3,4-dihydro-1H-pyrimidin-2-one 
• 135701-17-6 C₂₃H₂₇BrN₂O₂S 
• 134045-71-9 5-(4-Bromo-phenyl)-7-phenyl-3-p-tolylazo-pyrazolo[1,5-a]pyrimidin-2-ylamine 
• 134045-64-0 5-(4-Bromo-phenyl)-3-(4-chloro-phenylazo)-7-phenyl-pyrazolo[1,5-a]pyrimidin-2-ylamine 
• 134045-78-6 5-(4-Bromo-phenyl)-3-(4-methoxy-phenylazo)-7-phenyl-pyrazolo[1,5-a]pyrimidin-2-ylamine 
• 134045-58-2 5-(4-Bromo-phenyl)-7-phenyl-3-phenylazo-pyrazolo[1,5-a]pyrimidin-2-ylamine 
• 21067-52-7 4'-bromo-trans-chalcone-seqcis-oxime 
• 21067-52-7 (1E,2E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one oxime 
• 252668-08-9 (4-amino-1,2-diphenyl-5-thioxo-2,5-dihydro-1H-pyrrol-3-yl)-(4-bromo-phenyl)-methanone 
• 72997-91-2 4-(4-bromo-phenyl)-(trans-3-phenyl-aziridin-2-yl)-ketone 

Relevant articles and documents

Diastereoselective 1,3-dioxolane formation by photocatalytic ring opening of a-epoxyketones

Photocatalytic ring opening of α-epoxyketones by 2,3-dichloro-5,6- dicyano-1,4-benzoquinone (DDQ) in acetone resulted in the diastereoselective formation of 1,3-dioxolanes through Cα-O bond cleavage. The facility of the ring opening is influenced by the nature and the location of the additional substituent on the α-epoxyketones.

Orchestrating a β-Hydride Elimination Pathway in Palladium(II)-Catalyzed Arylation/Alkenylation of Cyclopropanols Using Organoboron Reagents

The scope of chemoselective β-hydride elimination in the context of arylation/alkenylation of homoenolates from cyclopropanol precursors using organoboronic reagents as transmetalation coupling partners was examined. The reaction optimization paradigm revealed a simple ligand-free Pd(II) catalytic system to be most efficient under open air conditions. The preparative scope, which was investigated with 48 examples, supported the applicability of this reaction to a wide range of substrates tolerating a variety of functional groups while delivering β-substituted enone and dienone derivatives in 62-95% yields.

Ag2CO3-catalyzed efficient synthesis of internal or terminal propargylicamines and chalcones via A3-coupling under solvent-free condition

Several simple, fast and practical protocols have been developed to synthesize internal or terminal propargylamines and chalcones via A3-coupling reaction of aldehydes, amines, and alkynes catalyzed by an easily available catalyst Ag2CO3 under solvent-free condition. The reaction proceeded smoothly to deliver various products in good-to-excellent yields with good functional group tolerance. Gram-scale preparation, bioactive molecule synthesis and asymmetric substrates have been demonstrated. Furthermore, plausible mechanisms for the synthesis of different products have been proposed.

Pyridoimidazole derivatives as well as preparation method and application thereof

The invention discloses pyridoimidazole derivatives as well as a preparation method and application thereof. The pyridoimidazole derivatives with two D-pi-A structures are synthesized on the basis that pyridoimidazole serves as an electron acceptor system by means of the electron donating property of phenanthroimidazole/diphenylamine. The pyridoimidazole derivatives can serve as photoinitiators, and the two photoinitiators both have longer conjugated chain lengths, so that the photon absorption cross section is increased, the photoinitiators can initiate polymerization reaction at the wavelength of 365 nm, have higher polymerization efficiency, and can be widely applied to the field of ultraviolet curing.