2503-55-1 Usage
Description
N-BENZYLNICOTINAMIDE is a chemical compound that belongs to the nicotinamide family, a derivative of nicotinamide, which is a form of vitamin B3. It is known for its antioxidant and neuroprotective properties and is commonly used in research and studies related to the treatment of neurological disorders, metabolic diseases, and cancer. N-BENZYLNICOTINAMIDE is also being investigated for its ability to improve mitochondrial function and energy metabolism, making it a promising candidate for therapeutic interventions targeting these pathways. Overall, N-benzylnicotinamide shows potential as a valuable compound for medicinal and pharmaceutical purposes.
Uses
Used in Pharmaceutical Industry:
N-BENZYLNICOTINAMIDE is used as a research compound for the development of new drugs for various medical conditions, particularly in the treatment of neurological disorders, metabolic diseases, and cancer.
Used in Neurological Disorders Research:
N-BENZYLNICOTINAMIDE is used as a neuroprotective agent in studies related to the treatment of neurological disorders, due to its antioxidant and neuroprotective properties.
Used in Metabolic Diseases Research:
N-BENZYLNICOTINAMIDE is used as a research compound in studies related to the treatment of metabolic diseases, given its potential to improve mitochondrial function and energy metabolism.
Used in Cancer Research:
N-BENZYLNICOTINAMIDE is used as a research compound in studies related to the treatment of cancer, as it has been shown to possess potential applications in this area.
Check Digit Verification of cas no
The CAS Registry Mumber 2503-55-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,0 and 3 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2503-55:
(6*2)+(5*5)+(4*0)+(3*3)+(2*5)+(1*5)=61
61 % 10 = 1
So 2503-55-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO/c10-7-9-6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H,9,10)
2503-55-1Relevant articles and documents
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Sperber et al.
, p. 2012,2014 (1950)
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Reductive N-alkylation of primary amides using nickel-nanoparticles
Alenad, Asma M.,Alshammari, Ahmad S.,Jagadeesh, Rajenahally V.,Murugesan, Kathiravan,Sohail, Manzar
, (2021/11/22)
Here we report Ni-nanoparticles as reusable catalysts for reductive N-alkylation of amides. These Ni-nanoparticles based catalysts have been prepared by the template synthesis of tartaric acid and 2-methyl imidazole ligated Ni-complex on SiO2 and subsequent pyrolysis under argon. Applying optimal Ni-nanostructured catalyst, N-alkylation of aromatic and heterocyclic primary amides with different aldehydes in presence of molecular hydrogen was performed to access structurally diverse N-alkylated amides in good to excellent yields. In addition, the applicability of this N-alkylation protocol has been demonstrated for the selective functionalization of primary amide group in Levetiracetam drug.
Graphene oxide: A convenient metal-free carbocatalyst for facilitating amidation of esters with amines
Patel, Khushbu P.,Gayakwad, Eknath M.,Shankarling, Ganapati S.
, p. 2661 - 2668 (2020/02/20)
Herein, we report a graphene oxide (GO) catalyzed condensation of non-activated esters and amines, that can enable diverse amides to be synthesized from abundant ethyl esters forming only volatile alcohol as a by-product. GO accelerates ester to amide conversion in the absence of any additives, unlike other catalysts. A wide range of ester and amine substrates are screened to yield the respective amides in good to excellent yields. The improved catalytic activity can be ascribed to the oxygenated functionalities present on the graphene oxide surface which forms H-bonding with the reactants accelerating the reaction. Improved yields and a wide range of functional group tolerance are some of the important features of the developed protocol.