250649-08-2Relevant articles and documents
Synthesis and reactions of Biginelli-compounds. Part 23: Chemoenzymatic syntheses of enantiomerically pure 4-aryl-3,4-dihydropyrimidin-2(1H)-ones
Schnell, Barbara,Krenn, Wolfram,Faber, Kurt,Kappe, C. Oliver
, p. 4382 - 4389 (2007/10/03)
Enantiomerically pure dihydropyrimidones (DHPMs) were prepared by lipase-catalyzed enzymatic resolution of two types of activated DHPM esters. In the first model series, pivaloyloxymethyl-activated DHPM C5-esters 10a-c were resolved on an analytical scale