253353-15-0

Basic information

• Product Name: 1,1-dimethylethyl (αS)-2,3-bis(1-methylethoxy)-γ-(1,1-dimethylethoxycarbonyl)-1-hydroxy-4-oxo-α-(phenylmethyloxycarbonylamino)-2-cyclobutene-1-butyrate
• Synonyms: 1,1-dimethylethyl (αS)-2,3-bis(1-methylethoxy)-γ-(1,1-dimethylethoxycarbonyl)-1-hydroxy-4-oxo-α-(phenylmethyloxycarbonylamino)-2-cyclobutene-1-butyrate
• CAS NO: 253353-15-0
• Molecular Weight: 591.699
• Mol File: 253353-15-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1-dimethylethyl (αS)-2,3-bis(1-methylethoxy)-γ-(1,1-dimethylethoxycarbonyl)-1-hydroxy-4-oxo-α-(phenylmethyloxycarbonylamino)-2-cyclobutene-1-butyrate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethylethyl (αS)-2,3-bis(1-methylethoxy)-γ-(1,1-dimethylethoxycarbonyl)-1-hydroxy-4-oxo-α-(phenylmethyloxycarbonylamino)-2-cyclobutene-1-butyrate(253353-15-0)
• EPA Substance Registry System: 1,1-dimethylethyl (αS)-2,3-bis(1-methylethoxy)-γ-(1,1-dimethylethoxycarbonyl)-1-hydroxy-4-oxo-α-(phenylmethyloxycarbonylamino)-2-cyclobutene-1-butyrate(253353-15-0)

Safety Data

• Hazardous Substances Data: 253353-15-0(Hazardous Substances Data)

Upstream product

• 61699-62-5 diisopropyl squarate 
• 16881-41-7 di-tert-butyl N-Cbz-L-glutamate 

Downstream Products

• 253353-16-1 1,1-dimethylethyl (αS)-γ-(1,1-dimethylethoxycarbonyl)-3,4-dioxo-2-(1-methylethoxy)-α-(phenylmethyloxycarbonylamino)-1-cyclobutene-1-butyrate 
• 253353-17-2 (αS)-3,4-dioxo-2-(1-methylethoxy)-α-phenylmethyloxycarbonylamino-1-cyclobutene-1-butyric acid 

Relevant articles and documents

Efficient synthesis of a novel 4-hydroxy-2,3-dioxocyclobut-1-enyl group containing amino acids

matrix presented Syntheses of novel amino acids possessing a squaryl group, 1-3, in an optically active form are described. The syntheses of 1-3 were conducted by a concise route involving (1) an aldol addition of an enolate derived from Gly, L-Asp, or L-Glu to diisopropyl squarate (4) and (2) an efficient decarboxylation of the aldol adducts based on the electron-withdrawing property of the squaryl group. Introducing N-protected group to 2 and 3 and peptide formation reactions are also described.