25347-94-8

Basic information

• Product Name: 1-tert-butyl-3-methylurea
• CAS NO: 25347-94-8
• Molecular Formula: C₆H₁₄N₂O
• Molecular Weight: 130.1882
• Mol File: 25347-94-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 249.3°C at 760 mmHg
• Flash Point: 111.5°C
• Density: 0.914g/cm³
• Vapor Pressure: 0.0231mmHg at 25°C
• Refractive Index: 1.433
• CAS DataBase Reference: 1-tert-butyl-3-methylurea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-tert-butyl-3-methylurea(25347-94-8)
• EPA Substance Registry System: 1-tert-butyl-3-methylurea(25347-94-8)

Safety Data

• Hazardous Substances Data: 25347-94-8(Hazardous Substances Data)

Usage

Type of compound

Urea derivative (specifically, a substituted urea)

Substituent groups

A tert-butyl group and a methyl group attached to the nitrogen atom

Common uses

Reagent in organic synthesis, pharmaceutical research

Potential applications

Corrosion inhibitor, stabilizer for explosives

Biological properties

Antifungal and antiviral properties

Importance

Versatile and valuable in scientific and industrial applications

Upstream product

• 95598-14-4 3-t-butyl-1-methyl-1-nitrosothiourea 
• 10016-20-3 alpha cyclodextrin 
• 3964-50-9 N-methyl-N'-tert-butylthiourea 
• 19411-70-2 N-tert-butyl-N'-methylcarbodiimide 
• 75-64-9 tert-butylamine 
• 624-83-9 methyl isocyanate 

Downstream Products

• 36801-14-6 1-Benzoyl-3-methyl-5-tert-butylbiuret 
• 72479-14-2 N-Methyl-N'-tert-butyl-N-nitrosourea 
• 36791-67-0 N-(4-tert-butylimino-3-methyl-[1,3]thiazetidin-2-ylidene)-toluene-4-sulfonamide 
• 36801-13-5 N-(3-tert-Butyl-1,2-dimethyl-isoureidocarbonyl)-benzamide 
• 23730-18-9 4-methyl-N-(tert-butylcarbamoyl)benzenesulfonamide 
• 590-42-1 tert-butyl isothiocyanate 
• 36791-65-8 N-tert-butyl-3-methyl-N'-(4-nitro-phenyl)-[1,3]thiazetidine-2,4-diylidenediamine 
• 80820-86-6 1-tert-Butyl-3-methyl-5-(2-tolyl)biuret 
• 80820-72-0 1-tert-Butyl-3-methyl-5-(4-tolyl)biuret 

Relevant articles and documents

An empirical estimation of the interactions Hδ+...Cl-. The crystal and molecular structure of the 1-methyl-2-tert-butylamino-4-isopropyl-5(4H)-imidazolone hydrochloride

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Electronic and Steric Effects of Alkyl Group on Denitrosation of 3-Alkyl-1-methyl-1-nitrosothioureas

A series of 3-alkyl-1-methyl-1-nitrosothioureas with R=CH3, C2H5, cyclo-C6H11 (3), (CH3)2CH (4), C2H5(CH3)CH, and (CH3)3C were synthesized and their rates of acid catalyzes (pHH:kD is 1.25 for 4.Except 3, a linear plot of log kR/kMe for the denitrosation of RNHCSN(NO)CH3 vs. ?* provides ρ*=-0.98(r=-0.997).The significant factor affecting the rate determining step of the denitrosation of these N-nitrosothioureas at pH 4.6 is the electronic effect of the substituent at the N3 position.

THE SYNTHESIS OF ANTINEOPLASTIC AGENTS. XXXII. N-NITROSOUREAS. I.

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