263272-39-5

Basic information

• Product Name: 4-{[3-[4-(2-bromo-benzyloxycarbonyloxy)-phenyl]-2-(6-tert-butoxycarbonylamino-hexanoylamino)-propionylamino]-methyl}-cyclohexanecarboxylic acid octyl ester
• Synonyms: 4-{[3-[4-(2-bromo-benzyloxycarbonyloxy)-phenyl]-2-(6-tert-butoxycarbonylamino-hexanoylamino)-propionylamino]-methyl}-cyclohexanecarboxylic acid octyl ester
• CAS NO: 263272-39-5
• Molecular Weight: 858.911
• Mol File: 263272-39-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-{[3-[4-(2-bromo-benzyloxycarbonyloxy)-phenyl]-2-(6-tert-butoxycarbonylamino-hexanoylamino)-propionylamino]-methyl}-cyclohexanecarboxylic acid octyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[3-[4-(2-bromo-benzyloxycarbonyloxy)-phenyl]-2-(6-tert-butoxycarbonylamino-hexanoylamino)-propionylamino]-methyl}-cyclohexanecarboxylic acid octyl ester(263272-39-5)
• EPA Substance Registry System: 4-{[3-[4-(2-bromo-benzyloxycarbonyloxy)-phenyl]-2-(6-tert-butoxycarbonylamino-hexanoylamino)-propionylamino]-methyl}-cyclohexanecarboxylic acid octyl ester(263272-39-5)

Safety Data

• Hazardous Substances Data: 263272-39-5(Hazardous Substances Data)

Upstream product

• 263272-35-1 4-({3-[4-(2-bromo-benzyloxycarbonyloxy)-phenyl]-2-tert-butoxycarbonylamino-propionylamino}-methyl)-cyclohexanecarboxylic acid octyl ester 
• 263272-44-2 carbonic acid 2-bromo-benzyl ester 4-(2-tert-butoxycarbonylamino-3-isobutoxycarbonyloxy-3-oxo-propyl)-phenyl ester 
• 47689-67-8 (S)-3-[4-(2-Bromo-benzyloxycarbonyloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid 
• 780693-21-2 4-Aminomethyl-cyclohexanecarboxylic acid octyl ester 
• 6404-29-1 6-(tert-butoxycarbonylamino)hexanoic acid 
• 263272-45-3 C₁₆H₂₉NO₆ 

Relevant articles and documents

Development of plasmin-selective inhibitors and studies of their structure-activity relationship

Various compounds were synthesized by combining three components at positions P1, P1, and P2,. Of these, N-(trans-4- aminomethylcyclohexanecarbonyl)-Tyr(O-2-bromobenzyloxycarbonyl)-octylamide inhibited plasmin selectively with IC50 values of 0.80 and 0.23 μM towards S-2251 and fibrin, respectively. This compound also inhibited plasma kallikrein, urokinase, thrombin and trypsin with IC50 values of 10, >50, >50 and 1.6 μM, respectively.