26850-28-2

Basic information

• Product Name: Glycine, N-(4-hydroxyphenyl)-, ethyl ester
• Synonyms: Aethylester aus 4-Oxy-anilinoessigsaeure;N-(4-Hydroxy-phenyl)-glycin-aethylester;N-(4-hydroxy-phenyl)-glycine ethyl ester;4-Oxy-anilinoessigsaeure-aethylester;ethyl p-hydroxy-phenylglycinate;ethyl D-p-hydroxyphenylglycinate
• CAS NO: 26850-28-2
• Molecular Formula: C10H13NO3
• Molecular Weight: 195.218
• Mol File: 26850-28-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Glycine, N-(4-hydroxyphenyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-(4-hydroxyphenyl)-, ethyl ester(26850-28-2)
• EPA Substance Registry System: Glycine, N-(4-hydroxyphenyl)-, ethyl ester(26850-28-2)

Safety Data

• Hazardous Substances Data: 26850-28-2(Hazardous Substances Data)

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 123-30-8 4-amino-phenol 
• 7664-93-9 sulfuric acid 
• 122-87-2 N-(hydroxyphenyl)glycine 
• 64-17-5 ethanol 

Downstream Products

• 1391490-71-3 ethyl 6-hydroxy-4-phenylquinoline-2-carboxylate 
• 122-87-2 N-(hydroxyphenyl)glycine 
• 88798-23-6 dibenzylammonium DL(+/-)-alpha-(N-pyrrolyl)-p-hydroxy-phenylacetate 

Relevant articles and documents

Preparation method of N-aryl glycine ester derivative

The invention relates to a preparation method of an N-aryl glycine ester derivative. The invention aims to solve the problems of complex steps and environmental pollution in the existing method for synthesizing the N-aryl glycine ester derivative. The preparation method comprises the following steps: dissolving an aryl primary amine compound, ethyl diazoacetate, a reaction aid and a photocatalystin an organic solvent at room temperature, uniformly mixing, reacting under a blue LEDs lamp, carrying out reduced pressure distillation to remove the solvent, and separating and purifying to obtain the product. The problems of high energy consumption, high cost and environmental pollution caused by high temperature, biocatalyst or metal organic framework required by the synthesis of the existingN-aryl glycine ester derivative are solved. A route for synthesizing the N-arylglycine ester derivative, which is green, efficient, mild in condition, simple in method, convenient to operate and highin yield, is found, and the method is applied to the field of organic synthesis.

Production of an ester of one enantiomer of an α-amino acid in the form of a salt with an optically active acid

A process for the production of an ester of one enantiomer of an α-amino acid in the form of a salt with an optically active acid, which comprises reacting an ester of the opposite enantiomer of said α-amino acid (which may be in admixture with an ester of the desired enantiomer) with said optically active acid and an aldehyde or ketone, whereby an ester of the desired enantiomer separates out in the form of the said salt. The free α-amino acid and/or its salts may be obtained by hydrolysis of the ester thus formed. Optically active α-amino acids and their esters are of use in the synthesis of physiologically active compounds e.g. antibiotics of the penicillin and cephalosporin types. The present invention provides a relatively cheap, high yield process for the production of esters of optically active α-amino acids and for the production of optically active α-amino acids thereform. Certain novel compounds are disclosed.