27593-40-4

Basic information

• Product Name: 3-Phenylglycidic acid tert-butyl ester
• Synonyms: 3-PHENYLGLYCIDIC ACID TERT-BUTYL ESTER;3-Phenyloxiranecarboxylic acid 1,1-dimethylethyl ester
• CAS NO: 27593-40-4
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.26
• Mol File: 27593-40-4.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 291 °C
• Flash Point: 118 °C
• Appearance: /
• Density: 1.125
• Vapor Pressure: 0.00197mmHg at 25°C
• Refractive Index: 1.526
• CAS DataBase Reference: 3-Phenylglycidic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenylglycidic acid tert-butyl ester(27593-40-4)
• EPA Substance Registry System: 3-Phenylglycidic acid tert-butyl ester(27593-40-4)

Safety Data

• Hazardous Substances Data: 27593-40-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H16O3/c1-13(2,3)16-12(14)11-10(15-11)9-7-5-4-6-8-9/h4-8,10-11H,1-3H3

Upstream product

• 14990-09-1 tert-butyl cinnamate 
• 75-91-2 tert.-butylhydroperoxide 
• 103-26-4 Methyl cinnamate 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 100-52-7 benzaldehyde 
• 107-59-5 tert-Butyl chloroacetate 
• 135980-98-2 t-butyl (2S,3S)-(+)-2-bromo-3-hydroxy-3-phenylpropionate 
• 60843-66-5 2,2-dimethyl-1-(3-phenyloxiran-2-yl)propan-1-one 
• 1415392-14-1 (2S,3R)-tert-butyl 3-chloro-2-hydroxy-3-phenylpropanoate 
• 62148-70-3 tert-butyl 3-chloro-2-oxo-3-phenylpropionate 
• 14990-09-1 tert-butyl cinnamate 

Downstream Products

• 136031-73-7 (2R,3R)-3-Azido-2-hydroxy-3-phenyl-propionic acid tert-butyl ester 
• 54885-10-8 sodium (E)-3-phenylglycidate 
• 7042-30-0 tert-butyl (Z)-3-phenyl-oxirane-2-carboxylate 
• 1415392-38-9 C₁₃H₁₅FO₃ 
• 135981-02-1 tert-butyl (2R,3R)-3-amino-2-hydroxy-3-phenylpropionate 
• 201804-25-3 t-butyl cis-β-phenylglycidate 
• 201804-27-5 (2R,3S)-tert-butyl 3-benzamido-2-hydroxy-3-phenylpropanoate 
• 201804-26-4 (2R,3S)-tert-butyl 3-azido-2-hydroxy-3-phenylpropanoate 
• 204587-97-3 (2R,3S)-3-Amino-2-hydroxy-3-phenyl-propionic acid tert-butyl ester 
• 132201-33-3 (2R,3S)-N-benzoyl-3-phenylisoserine 

Relevant articles and documents

Highly enantioselective bioinspired epoxidation of electron-deficient olefins with H2O2 on aminopyridine mn catalysts

The asymmetric epoxidation of various electron-deficient olefins with H2O2 in the presence of a novel family of chiral bioinspired bipyrrolidine-derived aminopyridine manganese(II) complexes [LM II(OTf)2] is rep

3- and 4-uloses derived from N-acetyl- D -glucosamine: A unique pair of complementary organocatalysts for asymmetric epoxidation of alkenes

The 4-ulose and the 3-ulose, both derived in two steps from the α-methyl glycoside of N-acetyl-D-glucosamine (GlcNAc), act as organocatalysts in the asymmetric epoxidation of alkenes, with unprecedented complementary enantioselectivity. The best results are found with α,β-unsaturated esters as substrates, with enantiomeric ratios up to 90:10 and 11:89, respectively. Copyright

Solid sodium hydroxide - THF, convenient system for synthesis esters of glycidic acids by darzens condensation

Isopropyl- and tert-butylchloroacetate react with carbonyl compounds in the presence of powdered sodium hydroxide in THF, without a catalyst, giving substituted glycidates. The process is applied for preparation of glycidates from ketones, hitherto unavailable by phase-transfer catalyzed Darzens condensation.