2761-09-3

Basic information

• Product Name: 3-hydroxypropyl methacrylate
• Synonyms: 3-hydroxypropyl methacrylate;2-Propenoic acid, 2-methyl-, 3-hydroxypropyl ester;1,3-Propanediol 1-methacrylate;1,3-Propanediol monomethacrylate;Dimethylolmethane methacrylate;Methacrylic acid 3-hydroxypropyl ester
• CAS NO: 2761-09-3
• Molecular Formula: C₇H₁₂O₃
• Molecular Weight: 144.16838
• EINECS: 220-426-2
• Mol File: 2761-09-3.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 213.5°Cat760mmHg
• Flash Point: 96.7°C
• Appearance: /
• Density: 1.03g/cm³
• Vapor Pressure: 0.0363mmHg at 25°C
• Refractive Index: 1.446
• PKA: 14.66±0.10(Predicted)
• CAS DataBase Reference: 3-hydroxypropyl methacrylate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxypropyl methacrylate(2761-09-3)
• EPA Substance Registry System: 3-hydroxypropyl methacrylate(2761-09-3)

Safety Data

• Hazardous Substances Data: 2761-09-3(Hazardous Substances Data)

Usage

General Description

3-Hydroxypropyl methacrylate (HPMA) is a colorless, liquid organic compound widely used in the field of polymer chemistry. It's classified as an ester of methacrylic acid containing a hydroxy group in its molecule, and its structure allows it to readily participate in various polymerization reactions. HPMA is mostly used as a monomer or comonomer in the production of polymer-based products due to its capability to produce polymers with water solubility, adhesion, and flexibility. It's also used in the manufacture of coatings, resins, plastics, and adhesive binders. However, it is flammable and may cause irritation to the skin or eyes, hence careful handling and safety measures are advised during its use.

InChI:InChI=1/C7H12O3/c1-6(2)7(9)10-5-3-4-8/h8H,1,3-5H2,2H3

Upstream product

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Relevant articles and documents

Programmed Degradation of Hydrogels with a Double-Locked Domain

The ability to control the degradation of a material is critical to various applications. The purpose of this study was to demonstrate a concept of controlling degradation by using a double-locked domain (DLD). DLDs are molecular structures with two functional units that work cooperatively under environmental stimulation. One unit is triggered to transform without cleavage in the presence of the first stimulus, but this transformation enables the activation of the other unit for cleavage in the presence of the second stimulus. A DLD is presented that is activated to transform through intramolecular reconfiguration when exposed to light. After this transformation, the light-triggered DLD can undergo rapid cleavage under acid treatment. When this DLD is used as the crosslinkers of hydrogels, hydrogels undergo rapid degradation after sequential exposure to light irradiation and acid treatment. Reversing the order of light irradiation and acid treatment or only using individual stimulation does not lead to comparable degradation. Thus, this study has successfully demonstrated the great potential of using DLDs to achieve programmable degradation of materials.

Predicting Monomers for Use in Polymerization-Induced Self-Assembly

We report an in silico method to predict monomers suitable for use in polymerization-induced self-assembly (PISA). By calculating the dependence of LogPoct /surface area (SA) on the length of the growing polymer chain, the change in hydrophobicity during polymerization was determined. This allowed for evaluation of the capability of a monomer to polymerize to form self-assembled structures during chain extension. Using this method, we identified five new monomers for use in aqueous PISA via reversible addition-fragmentation chain transfer (RAFT) polymerization, and confirmed that these all successfully underwent PISA to produce nanostructures of various morphologies. The results obtained using this method correlated well with and predicted the differences in morphology obtained from the PISA of block copolymers of similar molecular weight but different chemical structures. Thus, we propose this method can be utilized for the discovery of new monomers for PISA and also the prediction of their self-assembly behavior.

DENTAL CURABLE COMPOSITION

PROBLEM TO BE SOLVED: To provide a dental curable composition that promptly completes polymerization upon light irradiation. SOLUTION: A dental curable composition comprises: (A) a polymerizable monomer represented by general formula (1); and (B) a photoinitiator containing B1) an α-diketone compound, B2) a photoacid generator and B3) an aromatic amine compound. [X is -O-; Ar1 and Ar2 are divalent to tetravalent aromatic groups; L1 and L2 are divalent to tetravalent C2-60 hydrocarbon groups; R1 and R2 are hydrogen or methyl groups; and m1, m2, n1 and n2 are integers from 1 to 3.] SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT