28355-47-7

Basic information

• Product Name: Pyridine, 2-(3,5-dimethylphenoxy)-
• CAS NO: 28355-47-7
• Molecular Formula: C13H13NO
• Molecular Weight: 199.252
• Mol File: 28355-47-7.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Pyridine, 2-(3,5-dimethylphenoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2-(3,5-dimethylphenoxy)-(28355-47-7)
• EPA Substance Registry System: Pyridine, 2-(3,5-dimethylphenoxy)-(28355-47-7)

Safety Data

• Hazardous Substances Data: 28355-47-7(Hazardous Substances Data)

Upstream product

• 109-09-1 2-chloropyridine 
• 108-68-9 3,5-Dimethylphenol 
• 133604-82-7 3,5-dimethylphenyl 2-pyridinecarboxylate 
• 109-04-6 2-bromo-pyridine 

Downstream Products

• 5345-09-5 3,5-dimethyl-2-nitrophenol 
• 1590346-17-0 pentyl 2,4-dimethyl-6-(pyridin-2-yloxy)benzoate 

Relevant articles and documents

Copper(I)-USY as a Ligand-Free and Recyclable Catalyst for Ullmann-Type O-, N-, S-, and C-Arylation Reactions: Scope and Application to Total Synthesis

The copper(I)-doped zeolite CuI-USY proved to be a versatile, efficient, and recyclable catalyst for various Ullmann-type coupling reactions. Easy to prepare and cheap, this catalytic material enables the arylation and heteroarylation of diverse O-, N-, S-, and C-nucleophiles under ligand-free conditions while exhibiting large functional group compatibility. The facility of this catalyst to promote C-O bond formation was further demonstrated with the total synthesis of 3-methylobovatol, a naturally occurring diaryl ether of biological relevance. From a mechanistic viewpoint, two competitive pathways depending on the nature of the nucleophile and consistent with the obtained results have been proposed.

N-Picolinamides as ligands in Ullman type C–O coupling reactions

Copper-catalyzed modified Ullmann coupling reactions creating C–O bonds, including diaryl ethers or phenols, are vital to organic synthesis. Synthesized N-phenyl-2-pyridinecarboxamide and its derivatives were used as ligands in conjunction with catalytic copper sources in the formation of various diaryl ethers and phenols. Various aryl and heteroaryl halides with electron donating and withdrawing groups were reacted with various phenols under mild reaction conditions providing moderate to excellent yields.

A ortho-nitro phenol and its derivative synthesis method (by machine translation)

The invention relates to a method for the synthesis of organic compounds, in the existing technology of O-nitrophenol strong acid used in the synthesis process of the serious problem of environmental pollution and the synthesis step longer more complicated problem, the invention provides a ortho-nitro phenol and synthetic method of derivative thereof, proceeding by the phenol compound, synthesis of 2 - (phenoxy) pyridine, the obtained product, catalyst, tert-butyl nitrite, organic solvent and adding sealing in the pressure containers, in oil bath heating 50 - 100 °C, reaction 10 - 30 hours, to obtain 2 - (2 - nitrobenzene) ethoxy pyridine; re-processing by the ortho-nitro phenol and its derivatives; the method is simple, high-efficiency. (by machine translation)