28482-04-4Relevant articles and documents
Iridium-catalyzed enantioselective hydroalkynylation via alkene isomerization
Zhang, Wen-Wen,Li, Bi-Jie
, (2021)
An iridium-catalyzed enantioselective alkynylation of methylene C–H bonds γ to the amide group is developed. The reaction proceeds through alkene isomerization followed by regioselective hydroalkynylation. This method provides rapid access to a wide range of stereodefined alkynylated compounds in good yields and good enantioselectivities.
Self-Protection: The Advantage of Radical Oligomeric Mixtures in Organic Synthesis
Yu, Hui,Li, Chaozhong
, p. 142 - 145 (2007/10/03)
Atom-transfer radical oligomers of allyl iodoacetates were converted to 4-pentenoic acids upon treatment with zinc. Reactions of the radical oligomers of various ω-alkenyl iodoacetates with Grignard reagents afforded the corresponding substituted tetrahydrofuran derivatives. These results indicated that radical oligomeric mixtures not only serve as versatile intermediates in organic synthesis, but also exhibit unique advantages in that the oligomeric mixtures are self-protected and the deoligomerization functions as the simultaneous deprotection.