286437-63-6Relevant articles and documents
Use of libraries to access new chemical space: Applications to CRTH2
Masood, M. Abid,Gardner, Mark,Dack, Kevin,Winpenny, David,Lunn, Graham
scheme or table, p. 3682 - 3687 (2012/07/27)
The generation of novel CRTH2 ligands in heavily congested chemical space, by de novo design of libraries is disclosed. Novel (1719) compounds across seven libraries were synthesised. More than 100 of these compounds showed binding potency a viable one.
Partially protected novel trisphenols and process for production thereof
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, (2008/06/13)
The invention provides a partially protected trisphenol having the general formula (I) wherein R1is an alkyl group of 1-4 carbons or an alkoxyl group of 1-4 carbons, R2is an alkyl group of 1-6 carbons or a cycloalkyl group of 5 or 6 carbons, X1is a hydrogen atom, an alkoxycarbonylmethyl group wherein the alkyl group has 1-4 carbons, an alkoxycarbonyl group wherein the alkyl group has 1-4 carbons or a tetrahydropyranyl group, X2is a hydrogen atom, an alkoxycarbonylmethyl group wherein the alkyl group has 1-4 carbons, an alkoxycarbonyl group wherein the alkyl group has 1-4 carbons or a tetrahydropyranyl group, provided that when X1is a hydrogen atom, X2is not a hydrogen atom, and when X2is a hydrogen atom, X1is not a hydrogen atom; and m is an integer of 0, 1 or 2, and n is an integer of 0, 1, 2 or 3.