2882-19-1 Usage
Description
ETHYL ALPHA-BROMOPHENYLACETATE, also known as α-Bromobenzeneacetic acid ethyl ester, is an organic compound that serves as an alkyl halide initiator in various polymerization processes. It is characterized by its ability to initiate controlled/living radical polymerization, which allows for the synthesis of polymers with specific properties and structures.
Uses
Used in Polymer Synthesis:
ETHYL ALPHA-BROMOPHENYLACETATE is used as an alkyl halide initiator for the controlled/living radical polymerization of styrene and methyl methacrylate. This application is crucial for producing polymers with well-defined structures and properties, which can be tailored for specific applications in various industries.
Used in Chemical Synthesis:
Ethyl α-bromophenylacetate (EBPA) may be used to synthesize α-ethoxycarbonyl-N,α-diphenylnitrone, a compound with potential applications in various chemical and pharmaceutical processes.
Used in Polymerization of Dimethyl(methacryloyloxymethyl) Phosphonate:
ETHYL ALPHA-BROMOPHENYLACETATE is used as an initiator for the polymerization of dimethyl(methacryloyloxymethyl) phosphonate, a process that can lead to the development of polymers with specific properties, such as flame retardancy or improved thermal stability.
Used in Polymerization of Methyl Methacrylate (MMA):
As an initiator, ETHYL ALPHA-BROMOPHENYLACETATE is utilized in the polymerization of methyl methacrylate (MMA), a common monomer used to produce polymethyl methacrylate (PMMA), a versatile plastic material known for its transparency, rigidity, and weather resistance.
Used in Polymerization of Trimethylolpropane Triacrylate (TMPTA):
ETHYL ALPHA-BROMOPHENYLACETATE is also used as an initiator for the polymerization of trimethylolpropane triacrylate (TMPTA), a trifunctional monomer that can be used to produce highly crosslinked polymers with enhanced mechanical properties and chemical resistance.
Synthesis Reference(s)
Tetrahedron Letters, 13, p. 4067, 1972 DOI: 10.1016/S0040-4039(01)94239-X
Precautions
Moisture sensitive. Store away from oxidizing agents, air and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.
Check Digit Verification of cas no
The CAS Registry Mumber 2882-19-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,8 and 2 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2882-19:
(6*2)+(5*8)+(4*8)+(3*2)+(2*1)+(1*9)=101
101 % 10 = 1
So 2882-19-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H11BrO2/c1-2-13-10(12)7-8-5-3-4-6-9(8)11/h3-6H,2,7H2,1H3
2882-19-1Relevant articles and documents
PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS
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Paragraph 569-571, (2021/10/11)
The subject matter described herein is directed to pyruvate kinase activating compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds and methods of administering the compounds for the treatment of diseases associated with PKR and/or PKM2, such as pyruvate kinase deficiency, sickle cell disease, and beta-thalassemia.
Manganese-Catalyzed Dual-Deoxygenative Coupling of Primary Alcohols with 2-Arylethanols
Wang, Yujie,Shao, Zhihui,Zhang, Kun,Liu, Qiang
supporting information, p. 15143 - 15147 (2018/11/01)
Reported herein is a general and efficient dual-deoxygenative coupling of primary alcohols with 2-arylethanols catalyzed by a well-defined Mn/PNP pincer complex. This reaction is the first example of the catalytic dual-deoxygenation of alcohols using a non-noble-metal catalyst. Both deoxygenative homocoupling of 2-arylethanols (17 examples) and their deoxygenative cross-coupling with other primary alcohols (20 examples) proceeded smoothly to form the corresponding alkenes by a dehydrogenation and deformylation reaction sequence.
Application of piperazine structure containing compound to preparation of LSD1 (Lysine Specific Demethylase 1) inhibitor
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Paragraph 0028, (2017/09/29)
The invention discloses application of a piperazine structure containing compound to the preparation of a histone lysine specific demethylase (LSD1) inhibitor. The structural general formula of the compound is as shown in the following descriptions (wherein, A is hydrogen, carbonyl or thiocarbonyl) or a configurational isomer and a pharmaceutical salt thereof, or is as shown in the following descriptions or a pharmaceutical salt thereof. The compound has an obvious inhibition effect on the LSD1, can be prepared into the LSD1 inhibitor, and is used for preventing and treating a disease related to the activity of the histone LSD1.
