29182-45-4

Basic information

• Product Name: 2-Benzothiazoleacetic acid
• Synonyms: 2-Benzothiazoleaceticacid(7CI,8CI,9CI);1,3-benzothiazol-2-ylacetic acid;2-Benzothiazoleacetic acid;Benzothiazole-2-acetic acid;2-(benzo[d]thiazol-2-yl)acetic acid;(Benzo[d]thiazol-2-yl)-acetic acid;2-(Carboxymethyl)-1,3-benzothiazole;2-(1,3-benzothiazol-2-yl)acetic acid
• CAS NO: 29182-45-4
• Molecular Formula: C₉H₇NO₂S
• Molecular Weight: 193.22
• Product Categories: BENZOTHIAZOLE;Thiazole;Carboxylic Acids;Thiazoles, Isothiazoles & Benzothiazoles
• Mol File: 29182-45-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 112-113 °C
• Boiling Point: 380.867 °C at 760 mmHg
• Flash Point: 184.142 °C
• Appearance: /
• Density: 1.445 g/cm³
• Vapor Pressure: 1.76E-06mmHg at 25°C
• Storage Temp.: 2-8°C
• PKA: 0.58±0.30(Predicted)
• CAS DataBase Reference: 2-Benzothiazoleacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzothiazoleacetic acid(29182-45-4)
• EPA Substance Registry System: 2-Benzothiazoleacetic acid(29182-45-4)

Safety Data

• Hazardous Substances Data: 29182-45-4(Hazardous Substances Data)

Usage

General Description

2-Benzothiazoleacetic acid is a chemical compound with the molecular formula C10H7NOS. It is a derivative of benzothiazole and acetic acid, and is often used as a building block in the synthesis of various pharmaceuticals and agrochemicals. 2-Benzothiazoleacetic acid is known to exhibit anti-inflammatory and analgesic properties, making it potentially useful in the development of new drugs for pain relief or therapeutic treatments. Additionally, 2-Benzothiazoleacetic acid has shown potential as a corrosion inhibitor in metal surfaces, indicating its versatility in various industrial applications. However, further research and investigation are necessary to fully understand its potential benefits and applications.

InChI:InChI=1/C9H7NO2S/c11-9(12)5-8-10-6-3-1-2-4-7(6)13-8/h1-4H,5H2,(H,11,12)/p-1

Upstream product

• 46055-91-8 2-benzothiazol-2-yl-ethanol 
• 88638-49-7 2-(2-chloroethyl)benzo[d]thiazole 
• 141-82-2 malonic acid 
• 137-07-5 2-amino-benzenethiol 
• 3288-00-4 phenylthiocarbamoyl-malonic acid diethyl ester 
• 149-30-4 2-thioxo-3H-1,3-benzothiazole 
• 615-20-3 2-chlorobenzo[d][1,3]thiazole 
• 372-09-8 cyanoacetic acid 
• 29182-42-1 ethyl 2-(2-benzothiazolyl)acetate 
• 29198-44-5 1,3-diethyl 2-(1,3-benzothiazol-2-yl)propanedioate 
• 120-75-2 2-Methylbenzothiazole 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 120-75-2 2-Methylbenzothiazole 
• 38215-36-0 Coumarin 6 
• 131868-03-6 2-(benzo[d]thiazol-2-yl)-N-(4-methoxyphenyl)acetamide 
• 1383719-93-4 C₂₇H₃₃N₃O₂S 

Relevant articles and documents

Antibacterial and antitubercular activity of novel benzothiazole- aryl amine derivatives tethered through acetamide functionality

A novel series of substituted benzothiazole-N-phenyl acetamides were synthesized through a feasible scheme and characterized by IR, 1H NMR and mass spectral methods. All the synthesized compounds were screened for antibacterial activity against two, Gram-positive strains: Staphylococcus aureus, Bacillus subtilis; four, Gram-negative strains: Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa and Klebsiella pneumonia; and antitubercular activity against mycobacterial strain: Mycobacterium tuberculosis. Among the 15 compounds (6a-o) tested, three compounds 6e, 6l and 6m have demonstrated high potency with MIC values ranges from 6.25-12.5 μg/mL against both Gram-positive and Gram-negative strains. Compounds 6e and 6l displayed remarkable antitubercular activity with MIC value of 25μg/mL.

Substituted amide phenol compound and its preparation method, pharmaceutical composition and use thereof

The invention discloses substituted-amide phenolic compounds, their preparation method, a pharmaceutical composition and an application thereof. The compounds have a structure as shown in the general formula I, wherein Z, L and Q are as defined in the spe