294863-22-2

Basic information

• Product Name: (-)-(3S,4S)-4-(benzyloxy)-3-(tert-butyldimethylsilyloxy)pentan-1-ol
• Synonyms: (-)-(3S,4S)-4-(benzyloxy)-3-(tert-butyldimethylsilyloxy)pentan-1-ol
• CAS NO: 294863-22-2
• Molecular Weight: 324.536
• Mol File: 294863-22-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (-)-(3S,4S)-4-(benzyloxy)-3-(tert-butyldimethylsilyloxy)pentan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(3S,4S)-4-(benzyloxy)-3-(tert-butyldimethylsilyloxy)pentan-1-ol(294863-22-2)
• EPA Substance Registry System: (-)-(3S,4S)-4-(benzyloxy)-3-(tert-butyldimethylsilyloxy)pentan-1-ol(294863-22-2)

Safety Data

• Hazardous Substances Data: 294863-22-2(Hazardous Substances Data)

Downstream Products

• 335022-98-5 1-[(2S,3R)-2-benzyloxy-5-(2-naphthyloxy)-3-pentyl]imidazole-4-carboxamide 
• 294862-80-9 1-[(2S,3R)-2-benzyloxy-5-(tert-butyldimethylsilyloxy)-3-pentyl]imidazole-4-carboxamide 
• 294863-25-5 1-[(2S,3R)-2-benzyloxy-5-methylsulfonyloxy-3-pentyl]imidazole-4-carboxamide 
• 294863-24-4 1-[(2S,3R)-2-benzyloxy-5-hydroxy-3-pentyl]imidazole-4-carboxamide 
• 700363-47-9 (3S,4S)-4-benzyloxy-1-(tert-butyldimethylsilyloxy)pentan-3-ol 
• 294862-91-2 (3S,4S)-4-benzyloxypentane-1,3-diol 

Relevant articles and documents

Enantioselective synthesis of putative lipiarmycin aglycon related to fidaxomicin/tiacumicin B

An enantioselective synthesis of a putative lipiarmycin aglycon was accomplished and features: 1) Brown's enantioselective alkoxyallylboration and allylation of aldehydes, 2) chain elongation by iterative Horner-Wadsworth-Emmons olefination, 3) Evans' aldol reaction and 4) an enediene ring-closing metathesis. A neighboring-group-assisted chemoselective reductive desilylation was uncovered in this study and was instrumental to the realization of the present synthesis.