29632-73-3

Basic information

• Product Name: 2-Bromo-4-iodoaniline
• Synonyms: 2-Bromo-4-iodobenzenamine;2-Bromo-4-iodoaniline;2-Bromo-4-iodoanilin
• CAS NO: 29632-73-3
• Molecular Formula: C₆H₅BrIN
• Molecular Weight: 297.92
• Mol File: 29632-73-3.mol
• Article Data: 12

Chemical Properties

• Melting Point: 75-76 °C
• Boiling Point: 307.61°C at 760 mmHg
• Flash Point: 139.838°C
• Appearance: /
• Density: 2.292
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.715
• Storage Temp.: Refrigerated.
• CAS DataBase Reference: 2-Bromo-4-iodoaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-4-iodoaniline(29632-73-3)
• EPA Substance Registry System: 2-Bromo-4-iodoaniline(29632-73-3)

Safety Data

• Hazardous Substances Data: 29632-73-3(Hazardous Substances Data)

Usage

General Description

2-Bromo-4-iodoaniline is a chemical compound consisting of an aniline ring with a bromine and iodine atom attached to it. It is a light yellow to brown solid, and is commonly used as an intermediate in organic synthesis, particularly in the pharmaceutical industry. 2-Bromo-4-iodoaniline is known to be toxic if ingested, inhaled, or absorbed through the skin, and can cause irritation to the respiratory system and skin. It has also been found to have mutagenic and carcinogenic properties, making it a hazardous material that requires careful handling and disposal. Additionally, 2-Bromo-4-iodoaniline may cause environmental harm if released into water or soil. Due to its potentially harmful effects, proper precautions and safety measures should be taken when working with this chemical.

InChI:InChI=1/C6H5BrIN/c7-5-3-4(8)1-2-6(5)9/h1-3H,9H2

Upstream product

• 615-36-1 2-bromoaniline 
• 103-84-4 Acetanilid 
• 540-37-4 p-aminoiodobenzene 
• 474966-95-5 N-(2-bromo-4-iodophenyl)acetamide 

Downstream Products

• 873386-83-5 2-bromo-6-chloro-4-iodoaniline 
• 860556-79-2 2-bromo-1,4-diiodobenzene 

Relevant articles and documents

Bicyclic Phenyl–Ethynyl Architectures: Synthesis of a 1,4-Bis(phenylbuta-1,3-diyn-1-yl) Benzene Banister

The novel diacetylene bridged terphenylic macrocycle 1 is presented and discussed in the context of rotationally restricted “Gel?nder” oligomers. The 1,4-bis(phenylbuta-1,3-diyn-1-yl) benzene bridge of diacetylene 1 is significantly longer than its terphenyl backbone, forcing the bridge to bend around the central pylon. The synthesis of molecule 1 is based to a large extent on acetylene scaffolding strategies, profiting from orthogonal alkyne protection groups to close both macrocyclic subunits by oxidative acetylene coupling sequentially. The spatial arrangement and the dynamic enantiomerization process of the bicyclic target structure 1 are analyzed. In-depth NMR investigations not only reveal an unexpected spatial arrangement with both oligomer strands bent alongside the backbone, but also display the limited stability of the model compound in the presence of molecular oxygen.

Regioselective iodination of aryl amines using 1,4-dibenzyl-1,4-diazoniabicyclo [2.2.2] octane dichloroiodate in solution and under solvent-free conditions

1,4-Dibenzyl-1,4-diazoniabicyclo[2.2.2]octane dichloroiodate is an efficient and regioselective reagent for iodination of aryl amines. A wide variety of aryl amines in reaction with this reagent afforded regioselectively iodinated products. The iodination reaction can be carried out in solution or under solvent-free condition at room temperature.

Amplification of enantioselectivity and sensitivity based on non-linear response of molecular wire bearing pseudo-18-crown-6 to chiral amines

Exploiting a non-linear response for chiral discrimination, an intelligent system capable of chirality amplification was designed and constructed as poly(phenyleneethynylene) having chiral pseudo-18-crown-6. Both sensitivity and selectivity were amplified