315203-50-0

Basic information

• Product Name: L-Tyrosine, N-[(phenylmethoxy)carbonyl]-O-(phenylmethyl)-, phenylmethyl ester
• CAS NO: 315203-50-0
• Molecular Formula: C31H29NO5
• Molecular Weight: 495.575
• Mol File: 315203-50-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: L-Tyrosine, N-[(phenylmethoxy)carbonyl]-O-(phenylmethyl)-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Tyrosine, N-[(phenylmethoxy)carbonyl]-O-(phenylmethyl)-, phenylmethyl ester(315203-50-0)
• EPA Substance Registry System: L-Tyrosine, N-[(phenylmethoxy)carbonyl]-O-(phenylmethyl)-, phenylmethyl ester(315203-50-0)

Safety Data

• Hazardous Substances Data: 315203-50-0(Hazardous Substances Data)

Upstream product

• 86827-18-1 N-benzyloxycarbonyl-O-benzyl-L-tyrosine 
• 100-39-0 benzyl bromide 
• 600737-79-9 benzyl (S)-3-(4-(benzyloxy)-3-iodophenyl)-2-(((benzyloxy)carbonyl)amino)propanoate 
• 866114-87-6 (S)-2-Benzyloxycarbonylamino-3-(4-hydroxy-3,5-diiodo-phenyl)-propionic acid benzyl ester 
• 765908-37-0 C₃₁H₃₀BNO₇ 
• 5513-40-6 benzyl N-carbobenzyloxy-L-tyrosine 
• 70-78-0 3-Iodo-L-tyrosine 
• 501-53-1 benzyl chloroformate 
• 213757-66-5 (S)-2-Benzyloxycarbonylamino-3-(4-hydroxy-3-iodo-phenyl)-propionic acid benzyl ester 

Downstream Products

• 86827-18-1 N-benzyloxycarbonyl-O-benzyl-L-tyrosine 
• 600737-79-9 benzyl (S)-3-(4-(benzyloxy)-3-iodophenyl)-2-(((benzyloxy)carbonyl)amino)propanoate 
• 866114-88-7 (S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-3,5-diiodo-phenyl)-propionic acid benzyl ester 
• 765908-37-0 C₃₁H₃₀BNO₇ 
• 866115-07-3 (S)-3-{2'-Benzyloxy-5'-((S)-2-benzyloxycarbonyl-2-benzyloxycarbonylamino-ethyl)-5-[4-((S)-2-benzyloxycarbonyl-2-benzyloxycarbonylamino-ethyl)-phenoxy]-6-hydroxy-biphenyl-3-yl}-2-benzyloxycarbonylamino-propionic acid benzyl ester 
• 600737-82-4 (S)-2-Benzyloxycarbonylamino-3-[4-benzyloxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-propionic acid benzyl ester 
• 600737-85-7 (S)-2-Benzyloxycarbonylamino-3-[6,2'-bis-benzyloxy-5'-((S)-2-benzyloxycarbonyl-2-benzyloxycarbonylamino-ethyl)-biphenyl-3-yl]-propionic acid benzyl ester 

Relevant articles and documents

Synthesis of the side chain cross-linked tyrosine oligomers dityrosine, trityrosine, and pulcherosine

An efficient synthesis of dityrosine and the first syntheses of the tyrosine trimers trityrosine and pulcherosine have been achieved. Protected 3-iodotyrosine underwent tandem Miyaura borylation-Suzuki coupling to give protected dityrosine. The choice of

Pd/C(en)-catalyzed chemoselective hydrogenation with retention of the N-Cbz protective group and its scope and limitations

A chemoselective method for the hydrogenation of acetylene, olefin, azide, nitro and benzyl ester functionalities with retention of the aliphatic N-Cbz group was established. The chemoselectivity was accomplished by using a combination of 5% Pd/C-ethylenediamine [5% Pd/C(en)] and THF (or 1,4-dioxane) as a solvent, and the scope and limitations of this methodology were investigated. These results reinforce the utility of N-Cbz protective groups in synthetic chemistry, especially in peptide synthesis. (C) 2000 Elsevier Science Ltd.