32212-29-6

Basic information

• Product Name: 2-AMINO-N-ETHYLBENZAMIDE
• Synonyms: AKOS BBB/080;2-AMINO-N-ETHYLBENZAMIDE
• CAS NO: 32212-29-6
• Molecular Formula: C₉H₁₂N₂O
• Molecular Weight: 164.2
• Mol File: 32212-29-6.mol
• Article Data: 25

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-AMINO-N-ETHYLBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-N-ETHYLBENZAMIDE(32212-29-6)
• EPA Substance Registry System: 2-AMINO-N-ETHYLBENZAMIDE(32212-29-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 32212-29-6(Hazardous Substances Data)

Usage

Physical State

White to off-white solid

Structure

Contains a benzamide backbone with an amino group and an ethyl group attached to the benzene ring

Application

Used in the synthesis of various pharmaceutical and organic compounds

Usage

Building block in pharmaceutical and organic chemical production

Research

Utilized in research and development of new compounds

Potential Applications

Medicinal chemistry and drug discovery

Upstream product

• 118-48-9 isatoic anhydride 
• 75-04-7 ethylamine 
• 91-56-5 indole-2,3-dione 
• 1240143-95-6 2-amino-N-ethyl-N-[(5-methyl-2-furyl)methyl]benzamide 
• 610-14-0 2-nitrobenzyl chloride 
• 21563-73-5 2-aminobenzoyl chloride 
• 5344-90-1 2-Aminobenzyl alcohol 
• 28144-70-9 anthranilic acid amide 
• 118-92-3 anthranilic acid 

Downstream Products

• 308123-66-2 N-ethyl-2-(3-hydroxy-propylamino)-benzamide 
• 1385790-21-5 2-((1-acetyl-3-hydroxy-2-oxoindolin-3-yl)amino)-N-ethylbenzamide 
• 32212-30-9 N-Ethyl-2-amino-5-chlor-benzamid 
• 18343-46-9 2-Amino-3-chloro-N-ethyl-benzamide 
• 74375-38-5 3-ethyl-2-phenylquinazolin-4(3H)-one 
• 1769-24-0 2-methyl-4-quinazolone 
• 36244-13-0 3-(4-methoxyphenyl)-2-(trifluoromethyl)quinazolin-4(3H)-one 
• 36244-10-7 3-(p-tolyl)-2-(trifluoromethyl)quinazolin-4(3H)-one 
• 74375-39-6 3-ethyl-2-(p-tolyl)quinazolin-4(3H)-one 
• 1263413-49-5 2-[(chloroacetyl)amino]-N-ethylbenzamide 
• 220383-19-7 1-[N-(2-ethylaminocarbonylphenyl)-2-aminoethyl]-4-(2-methoxyphenyl)piperazine 

Relevant articles and documents

Palladium-catalyzed atroposelective coupling-cyclization of 2-isocyanobenzamides to construct axially chiral 2-aryl- And 2,3-diarylquinazolinones

A palladium-catalyzed imidoylative cycloamidation of N-alkyl-2-isocyanobenzamides with 2,6-disubstituted aryl iodides, affording unprecedented axially chiral 2-arylquinazolinones, has been developed with good yields and atroposelectivities. In this coupling-cyclization process, the biaryl linkage and the heteroaromatic ring are formed sequentially in one step. When N-(2,4dimethoxyphenyl)-2-isocyanobenzamide is applied as a substrate, 2,3-diarylquinazolinones containing two stereogenic axes are produced with moderate diastereoselectivity and good enantioselectivities.

Green synthesis of novel phosphonate derivatives using ultrasonic irradiation

[Figure not available: see fulltext.] A novel and efficient procedure for the generation of quinazolinone phosphonate derivatives employing the reaction of euparin, isatin or its derivatives, primary amines, dialkyl acetylenedicarboxylates, trimethyl phosphite or triphenyl phosphite, and acidic solution of hydrogen peroxide in aqueous media at ambient temperature under ultrasonic irradiation was developed. Without ultrasonic irradiation, the reaction does not proceed and agitation of the reaction mixture is difficult. Some advantages of this procedure are: short time of reaction, high yields of products, easy isolation of products.

NaNO2/I2 as an alternative reagent for the synthesis of 1,2,3-benzotriazin-4(3H)-ones from 2-aminobenzamides

An efficient transformation of 2-aminobenzamides to 1,2,3-benzotriazin-4(3H)-ones in the presence of sodium nitrite (NaNO2) and Iodine (I2) is described. The reaction is proposed to proceed via formation of nitrosyl halide that induces nitrosylation of the amino group of 2-aminobenzamide leading to diazotization followed by intramolecular cyclization.