32861-51-1

Basic information

• Product Name: Benzenepropanamine, N-(phenylmethyl)-
• CAS NO: 32861-51-1
• Molecular Formula: C16H19N
• Molecular Weight: 225.334
• Mol File: 32861-51-1.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: Benzenepropanamine, N-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamine, N-(phenylmethyl)-(32861-51-1)
• EPA Substance Registry System: Benzenepropanamine, N-(phenylmethyl)-(32861-51-1)

Safety Data

• Hazardous Substances Data: 32861-51-1(Hazardous Substances Data)

Upstream product

• 32861-47-5 N-(3-phenylpropylidene)benzylamine 
• 122-97-4 3-Phenyl-1-propanol 
• 100-39-0 benzyl bromide 
• 100-42-5 styrene 
• 201230-82-2 carbon monoxide 
• 100-46-9 benzylamine 
• 57152-94-0 N-benzylcinnamamide 
• 35960-75-9 N-(3-phenylpropyl)benzamide 
• 2038-57-5 3-Phenylpropan-1-amine 
• 98-88-4 benzoyl chloride 
• 145602-77-3 ethyl-(N,N-dibenzylamino)methyl-ether 
• 103-49-1 dibenzylamine 
• 65130-83-8 N-benzyl-N-methylene-1-phenylmethanaminium chloride 
• 104-53-0 3-phenyl-propionaldehyde 

Downstream Products

• 945714-78-3 NTR-N₄A₂B₅ 
• 53578-37-3 N-benzyl-3-phenylpropylamine hydrochloride 
• 70959-74-9 5-[1-Hydroxy-2-(3-phenyl-propylamino)-propyl]-2-methoxy-benzenesulfonamide 

Relevant articles and documents

BF3·Et2O as a metal-free catalyst for direct reductive amination of aldehydes with amines using formic acid as a reductant

A versatile metal- and base-free direct reductive amination of aldehydes with amines using formic acid as a reductant under the catalysis of inexpensive BF3·Et2O has been developed. A wide range of primary and secondary amines and diversely substituted aldehydes are compatible with this transformation, allowing facile access to various secondary and tertiary amines in high yields with wide functional group tolerance. Moreover, the method is convenient for the late-stage functionalization of bioactive compounds and preparation of commercialized drug molecules and biologically relevant N-heterocycles. The procedure has the advantages of simple operation and workup and easy scale-up, and does not require dry conditions, an inert atmosphere or a water scavenger. Mechanistic studies reveal the involvement of imine activation by BF3and hydride transfer from formic acid.

Sequential hydroaminomethylation/Pd-catalyzed hydrogenolysis as an atom efficient route to valuable primary and secondary amines

The facile synthesis of valuable primary and secondary amines is reported using a sequential procedure of hydroaminomethylation and Pd-catalyzed hydrogenolysis. The hydroaminomethylation reaction was catalyzed by a cationic Rh(I) iminopyridyl complex and the N-alkylated benzylamines were produced with high chemoselectivity, albeit as mixtures of linear and branched products. Performing the hydrogenolysis reaction using 10% Pd/C, provided access to valuable primary and secondary amines which have applications in the surfactant, pharmaceutical and polymer industries.

One-Pot Controlled Reduction of Conjugated Amides by Sequential Double Hydrosilylation Catalyzed by an Iridium(III) Metallacycle

A single and accessible cationic iridiumIII metallacycle effectively catalyzes the one-pot sequential double hydrosilylation of challenging α,β-unsaturated secondary and tertiary amides to afford, in a controlled and straightforward way, the co